ArticleEuropean heart journal open2022
Endometriosis and cardiovascular disease.
Article in European heart journal open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Endometriosis and risk of cardiovascular disease: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- The deviations of CD4 + T cells during peripheral blood and peritoneal fluid of endometriosis: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2023Pooled it
- Association between endometriosis and cardiovascular disease: a population-based cohort study.Journal of global health · 2026Article
- Review
- Association Between Endometriosis and Cardiovascular Disease: Insights From the UK Biobank.Journal of the American Heart Association · 2026Article
- Bioactive factors in endometriosis peritoneal fluid remodel human cardiomyocytes.American journal of physiology. Heart and circulatory physiology · 2026Article
- Cardiovascular Health in Women-Across the Lifespan.Clinical endocrinology · 2026Review
- SGLT2 Inhibitors and Mortality in Endometriosis With Type 2 Diabetes: A Propensity-Matched Analysis.JACC. Advances · 2026Article
- Endometriosis, subclinical cardiac remodeling, and cardiovascular risk: mechanistic insights from cardiac magnetic resonance and mediation analysis.Reproductive biology and endocrinology : RB&E · 2026Article
- Relationship between endometriosis diagnosis, staging, and typology and inflammatory cytokines.F&S reports · 2026Article
- Beyond the conventional risk factors in the management of atherosclerosis in women: a call to action for careful consideration of obesity and inflammation.European heart journal open · 2026Review
- Endometrial thickness evaluation with ultrasonography assessment among normal and endometrial cancer across multi-ethnic Indonesian women.Frontiers in reproductive health · 2026Article
- Menopause Hormone Therapy in Women With Cardiovascular Risk Factors or Established Ischemic Heart Disease: A Joint FIGO and WHF Position Paper.Global heart · 2026Review
- From Gynecological Endocrine Disorders to Cardiovascular Risk: Insights from Rat Models.Biomedicines · 2025Review
- Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Arquivos brasileiros de cardiologia · 2025Article
- Endometriosis and hypertriglyceridemia: Why do we care about severity and typology?The Utah women's health review · 2025Article
- Association between lipid accumulation product and visceral adiposity index with endometriosis: evidence from NHANES 1999-2006.BMC women's health · 2025Article
- The Role of miRNA in Endometriosis-Related Infertility-An Update.International journal of molecular sciences · 2025Review
- Study on the relationship between the non-HDL/HDL cholesterol ratio (NHHR) and endometriosis: a cross-sectional analysis utilizing the NHANES dataset.Lipids in health and disease · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a chronic gynaecological disease affecting 1 in 10 reproductive-age women. It is defined as the presence of endometrium-like tissue outside the uterus. Beyond this placid anatomical definition, endometriosis is a complex, hormonal, inflammatory, and systemic condition that poses significant familial, psychological, and economic burden. The interaction between the cardiovascular system and endometriosis has become a field of interest as the underlying mutual mechanisms become better understood. On the basis of accumulating fundamental and clinical evidence, it is likely that there exists a close relationship between endometriosis and the cardiovascular system. Therefore, investigating the endometriosis-cardiovascular interaction is highly clinically significant. In this review, we highlight our current understanding of the pathophysiology of endometriosis with systemic hormonal, pro-inflammatory, pro-angiogenic, immunologic, and genetic processes beyond the peritoneal microenvironment. Additionally, we provide current clinical evidence about how endometriosis interacts with cardiovascular risk factors and cardiovascular disease (CVD). To date, only small associations between endometriosis and CVD have been reported in observational studies, inherently limited by the potential influence of unmeasured confounding. Cardiovascular disease in women with endometriosis remains understudied, under-recognized, and underdiagnosed. More detailed study of the cardiovascular-endometriosis interaction is needed to fully understand its clinical relevance, underlying pathophysiology, possible means of early diagnosis and prevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.