Evidence map›Paper›PMID 35919467›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2022

Estimation of defined daily doses of antimicrobials for dogs and cats treated for bacterial cystitis.

J Scott Weese, Philip J Bergman, Ian Battersby, Talon McKee, Dennis Ballance, Anne Kimmerlein

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J Scott WeeseCentre for Public Health and Zoonoses, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada (Weese); VCA Clinical Studies, Los Angeles, California, USA (Bergman, McKee, Ballance, Battersby); Davies Veterinary Specialists, Hitchin, Hertfordshire, UK (Battersby); VCA Inc, Sacramento, California, USA (Kimmerlein).
Philip J BergmanCentre for Public Health and Zoonoses, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada (Weese); VCA Clinical Studies, Los Angeles, California, USA (Bergman, McKee, Ballance, Battersby); Davies Veterinary Specialists, Hitchin, Hertfordshire, UK (Battersby); VCA Inc, Sacramento, California, USA (Kimmerlein).
Ian BattersbyCentre for Public Health and Zoonoses, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada (Weese); VCA Clinical Studies, Los Angeles, California, USA (Bergman, McKee, Ballance, Battersby); Davies Veterinary Specialists, Hitchin, Hertfordshire, UK (Battersby); VCA Inc, Sacramento, California, USA (Kimmerlein).
Talon McKeeCentre for Public Health and Zoonoses, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada (Weese); VCA Clinical Studies, Los Angeles, California, USA (Bergman, McKee, Ballance, Battersby); Davies Veterinary Specialists, Hitchin, Hertfordshire, UK (Battersby); VCA Inc, Sacramento, California, USA (Kimmerlein).
Dennis BallanceCentre for Public Health and Zoonoses, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada (Weese); VCA Clinical Studies, Los Angeles, California, USA (Bergman, McKee, Ballance, Battersby); Davies Veterinary Specialists, Hitchin, Hertfordshire, UK (Battersby); VCA Inc, Sacramento, California, USA (Kimmerlein).
Anne KimmerleinCentre for Public Health and Zoonoses, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada (Weese); VCA Clinical Studies, Los Angeles, California, USA (Bergman, McKee, Ballance, Battersby); Davies Veterinary Specialists, Hitchin, Hertfordshire, UK (Battersby); VCA Inc, Sacramento, California, USA (Kimmerlein).
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To calculate prescribed daily doses (PDDs) for selected antimicrobials and evaluate application of defined daily doses (DDDs) using an antimicrobial purchasing dataset. Animals: Data from dogs and cats treated for bacterial cystitis at a veterinary practice network were evaluated. Procedure: A dataset containing antimicrobial prescriptions for dogs and cats diagnosed with bacterial cystitis was evaluated. Median dose and frequency and median weight of treated animals were used to calculate PDDs. To account for differences in use between dogs and cats, an adjusted DDD was calculated based on adjustment for proportional use in dogs Results: PDDs for dogs and cats were determined and adjusted DDDs were calculated and applied to an antimicrobial purchasing dataset from 886 veterinary clinics, demonstrating the difference between mass-based and DDD data. Conclusions: DDDs can be estimated using prescription datasets, accounting for differences in weights (between and within species) and relative use between dogs and cats. These can be applied to broader (sales, purchase) datasets to provide a more detailed understanding of how antimicrobials are used. Clinical relevance: DDDs could be a useful measure for assessing mass-based antimicrobial use datasets as part of antimicrobial stewardship surveillance efforts.

Indexed as

Anti-Infective AgentsBacterial InfectionsCat DiseasesCystitisDog DiseasesAnimalsAnti-Bacterial AgentsCatsDogsAnti-Bacterial AgentsAnti-Infective Agents

Identifiers

PMID35919467
PMCPMC9281882
OpenAlexW4289781761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.