Evidence map›Paper›PMID 35919437›Full record

ArticleChemical science2022

Simultaneous Raman and infrared spectroscopy: a novel combination for studying bacterial infections at the single cell level.

Cassio Lima, Shwan Ahmed, Yun Xu, Howbeer Muhamadali, Christopher Parry, Rachel J McGalliard, Enitan D Carrol, Royston Goodacre

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Plant and microbial sciences as key drivers in the development of metabolomics research.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Review
  18. Host Response Biomarkers for Sepsis in the Emergency Room.Critical care (London, England) · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Cassio LimaCentre for Metabolomics Research, Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool Liverpool L69 7ZB UK roy.goodacre@liverpool.ac.uk.ORCID https://orcid.org/0000-0002-9062-6298
Shwan AhmedCentre for Metabolomics Research, Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool Liverpool L69 7ZB UK roy.goodacre@liverpool.ac.uk.ORCID https://orcid.org/0000-0003-1289-442X
Yun XuCentre for Metabolomics Research, Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool Liverpool L69 7ZB UK roy.goodacre@liverpool.ac.uk.ORCID https://orcid.org/0000-0003-3228-5111
Howbeer MuhamadaliCentre for Metabolomics Research, Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool Liverpool L69 7ZB UK roy.goodacre@liverpool.ac.uk.ORCID https://orcid.org/0000-0002-1665-4717
Christopher ParryDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool Liverpool L69 7BE UK.
Rachel J McGalliardDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool Liverpool L69 7BE UK.ORCID https://orcid.org/0000-0003-0320-9945
Enitan D CarrolDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool Liverpool L69 7BE UK.ORCID https://orcid.org/0000-0001-8357-7726
Royston GoodacreCentre for Metabolomics Research, Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool Liverpool L69 7ZB UK roy.goodacre@liverpool.ac.uk.ORCID https://orcid.org/0000-0003-2230-645X
University of Liverpool · GB

Funding

Medical Research Council MR/S010483/1Wellcome Trust
6 · The paper itself

Abstract

Sepsis is a life-threatening clinical condition responsible for approximately 11 million deaths worldwide. Rapid and accurate identification of pathogenic bacteria and its antimicrobial susceptibility play a critical role in reducing the morbidity and mortality rates related to sepsis. Raman and infrared spectroscopies have great potential to be used as diagnostic tools for rapid and culture-free detection of bacterial infections. Despite numerous reports using both methods to analyse bacterial samples, there is to date no study collecting both Raman and infrared signatures from clinical samples simultaneously due to instrument incompatibilities. Here, we report for the first time the use of an emerging technology that provides infrared signatures

Identifiers

PMID35919437
PMCPMC9278432
OpenAlexW4285232044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.