Evidence map›Paper›PMID 35919388›Full record

ArticleRussian journal of bioorganic chemistry2022

Synthesis, Antiviral, and Antibacterial Activity of the Glycyrrhizic Acid and Glycyrrhetinic Acid Derivatives.

E A H Mohammed, Y Peng, Z Wang, X Qiang, Q Zhao

Open access · bronzeAbstract read
In one paragraph

Article in Russian journal of bioorganic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

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  13. Review on the Diverse Biological Effects of Glabridin.Drug design, development and therapy · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

E A H MohammedInstitute of Medicinal Chemistry, School of Pharmacy of Lanzhou University, 730000 Lanzhou, China.
Y PengInstitute of Medicinal Chemistry, School of Pharmacy of Lanzhou University, 730000 Lanzhou, China.
Z WangInstitute of Medicinal Chemistry, School of Pharmacy of Lanzhou University, 730000 Lanzhou, China.
X QiangInstitute of Medicinal Chemistry, School of Pharmacy of Lanzhou University, 730000 Lanzhou, China.
Q ZhaoInstitute of Medicinal Chemistry, School of Pharmacy of Lanzhou University, 730000 Lanzhou, China.
Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycyrrhizic acid and its primary metabolite glycyrrhetinic acid, are the main active ingredients in the licorice roots (glycyrrhiza species), which are widely used in several countries of the world, especially in east asian countries (China, Japan). These ingredients and their derivatives play an important role in treating many diseases, especially infectious diseases such as COVID-19 and hepatic infections. This review aims to summarize the different ways of synthesising the amide derivatives of glycyrrhizic acid and the main ways to synthesize the glycyrrhitinic acid derivatives. Also, to determine the main biological and pharmacological activity for these compounds from the previous studies to provide essential data to researchers for future studies. Supplementary Information: The online version contains supplementary material available at 10.1134/S1068162022050132.

Indexed as

anti-bacterial activityanti-coronavirusanti-viral activityglycyrrhitinic acidglycyrrhizic acid

Identifiers

PMID35919388
PMCPMC9333650
OpenAlexW4288722421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.