ReviewFood science and biotechnology2022
Calcium supplements and structure-activity relationship of peptide-calcium chelates: a review.
Review in Food science and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Preparation optimization, structural characterization, stability and promoting calcium absorption mechanism of sturgeon cartilage peptide-calcium chelates.Food chemistry: X · 2026Article
- Plant-based macronutrients and micronutrients in combating osteoporosis: research insights and molecular pathways.RSC advances · 2026Review
- Leaf nutritional composition and calcium speciation of a karst-endemic wild vegetable used by the indigenous people of Hainan Island, China.Frontiers in nutrition · 2026Article
- Food-derived protein-based calcium chelates: digestive stability, intestinal transport, and bone-related functions.Frontiers in nutrition · 2026Review
- The binding mechanism of a novel ferrous ion chelating peptide from chicken blood hemoglobin and the bioavailability of the chelate.Food chemistry: X · 2025Article
- Preparation, Structural Characterization, and Calcium Supplementation Activity ofFoods (Basel, Switzerland) · 2025Article
- Zinc Chelates from Low-Molecular-Weight Donkey-Hide Gelatin Peptides: Preparation, Characterization, and Evaluation of In Vitro Antioxidant Activity.Foods (Basel, Switzerland) · 2025Article
- Study on the Calcium Transport-Promoting Property and Mechanism of the Peptide-Calcium Complex DEEENDQVK-Ca Based on a Caco-2 Monolayer Model.Foods (Basel, Switzerland) · 2025Article
- Tracking the Effect of Phosvitin (PV) Concentration on the Skin Permeation of Somatotropin (STH) from Semi-Solid Hydrogel Formulations.Polymers · 2025Article
- Structural, antioxidant activity, and stability studies of jellyfish collagen peptide-calcium chelates.Food chemistry: X · 2024Article
- Optimization of the Preparation Process and Ameliorative Efficacy in Osteoporotic Rats of Peptide-Calcium Chelates from Skipjack Tuna (Foods (Basel, Switzerland) · 2024Article
- Preparation of Calcium-Binding Peptides Derived from Mackerel (Foods (Basel, Switzerland) · 2024Article
- Evaluating the capability of soybean peptides as calcium ion carriers: a study through sequence analysis and molecular dynamics simulations.RSC advances · 2024Article
- Study on the Changes of Bone Calcium during the Fermentation of Bone Powders with Different Fermenters.Foods (Basel, Switzerland) · 2024Article
- Effects of different manganese sources on nutrient digestibility, fecal bacterial community, and mineral excretion of weaning dairy calves.Frontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, the functional properties of peptides derived from food proteins have attracted considerable interest. Among them, bioactive peptides that can effectively bind metals have application prospects in the improvement of mineral bioavailability, and compensating for the shortcomings of the generally low bioavailability of inorganic mineral supplements. Although a reasonable understanding of structure activity relationship related to the calcium binding of peptides has been gained, physiological connections of peptides as mineral carriers to gastrointestinal uptake needs further research. Hence, this article reviews (1) the development of calcium supplements; (2) inorganic calcium sources and bone calcium; (3) source and acquisition of biologically active peptides; (4) calcium peptide chelation mechanism and structure-activity relationship; and (5) Methods for evaluating calcium bioavailability.
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