Evidence map›Paper›PMID 35919267›Full record

ArticleEuropean heart journal open2021

Segmental assessment of blood flow efficiency in the total cavopulmonary connection using four-dimensional flow magnetic resonance imaging: vortical flow is associated with increased viscous energy loss rate.

Friso M Rijnberg, Joe F Juffermans, Mark G Hazekamp, Willem A Helbing, Hildo J Lamb, Arno A W Roest, Jos J M Westenberg, Hans C van Assen

Open access · goldAbstract read
In one paragraph

Article in European heart journal open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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  12. Haemodynamic performance of 16-20-mm extracardiac Goretex conduits in adolescent Fontan patients at rest and during simulated exercise.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2022
    Article
  13. 4D flow cardiovascular magnetic resonance derived energetics in the Fontan circulation correlate with exercise capacity and CMR-derived liver fibrosis/congestion.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
  14. Open Up your Science inEuropean heart journal open · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Friso M RijnbergDepartment of Cardiothoracic Surgery, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, the Netherlands.ORCID https://orcid.org/0000-0003-1804-3220
Joe F JuffermansDepartment of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, the Netherlands.
Mark G HazekampDepartment of Cardiothoracic Surgery, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, the Netherlands.
Willem A HelbingDivision of Pediatric Cardiology, Department of Pediatrics, Erasmus University Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, the Netherlands.
Hildo J LambDepartment of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, the Netherlands.
Arno A W RoestDepartment of Pediatric Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, the Netherlands.ORCID https://orcid.org/0000-0002-0153-5934
Jos J M WestenbergDepartment of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, the Netherlands.
Hans C van AssenDepartment of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333ZA Leiden, the Netherlands.
Leiden University Medical Center · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To study flow-related energetics in multiple anatomical segments of the total cavopulmonary connection (TCPC) in Fontan patients from four-dimensional (4D) flow magnetic resonance imaging (MRI), and to study the relationship between adverse flow patterns and segment-specific energetics. Methods and results: Twenty-six extracardiac Fontan patients underwent 4D flow MRI of the TCPC. A segmentation of the TCPC was automatically divided into five anatomical segments [conduit, superior vena cava (SVC), right/left pulmonary artery (LPA), and the Fontan confluence]. The presence of vortical flow in the pulmonary arteries or Fontan confluence was qualitatively scored. Kinetic energy (KE), viscous energy loss rate, and vorticity were calculated from the 4D flow MRI velocity field and normalized for segment length and/or inflow. Energetics were compared between segments and the relationship between vortical flow and segment cross-sectional area (CSA) with segment-specific energetics was determined. Vortical flow in the LPA ( Conclusions: Vortical flow in the Fontan confluence and LPA associated with significantly increased viscous energy loss rate. Four-dimensional flow MRI-derived energetics may be used as a screening tool for direct, MRI-based assessment of flow efficiency in the TCPC.

Indexed as

4D flow MRIEnergeticsFontanTotal cavopulmonary connectionViscous energy loss, vortex

Identifiers

PMID35919267
PMCPMC9241567
OpenAlexW3191995306

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.