Evidence map›Paper›PMID 35919050›Full record

ArticleQuantitative imaging in medicine and surgery2022

Correlation between apparent diffusion coefficient and tumor-stroma ratio in hybrid

Shidong Hu, Xiaowei Xing, Jiajin Liu, Xi Liu, Jinhang Li, Wei Jin, Songyan Li, Yang Yan, Da Teng, Boyan Liu and 3 more

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. The value ofQuantitative imaging in medicine and surgery · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shidong Hu *Department of General Surgery, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Xiaowei Xing *Department of Hernia and Abdominal Wall Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Jiajin Liu *Department of Nuclear Medicine, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Xi LiuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Radiology, Peking University Cancer Hospital and Institute, Beijing, China.
Jinhang LiDepartment of Pathology, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Wei JinDepartment of Pathology, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Songyan LiDepartment of General Surgery, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Yang YanDepartment of General Surgery, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Da TengDepartment of General Surgery, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Boyan LiuDepartment of General Surgery, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Yufeng WangDepartment of Hospital Management, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Baixuan Xu *Department of Nuclear Medicine, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Xiaohui Du *Department of General Surgery, The First Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To explore possible correlations between the tumor-stroma ratio (TSR) and different imaging features of fluorine-18-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ( Methods: A patients with rectal cancer were included in this study. All participants were examined preoperatively with whole-body Results: Our results showed that in the untreated rectal cancer patients, the ADC mean values correlated with the TSR (r=0.327; P=0.007), and stroma-high (low TSR) rectal cancer corresponded to relatively lower ADC mean values (813.54±88.68 Conclusions: This study indicated that the intratumoral heterogeneity measured by PET/MRI may reflect characteristics of the tumor microenvironment. Hence, PET/MRI parameters might be helpful in predicting tumor aggressiveness and prognosis.

Indexed as

apparent diffusion coefficient (ADC)positron emission tomography/magnetic resonance imaging (PET/MRI)Rectal cancertumor-stroma ratio (TSR)

Identifiers

PMID35919050
PMCPMC9338373

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.