Evidence map›Paper›PMID 35919043›Full record

ArticleQuantitative imaging in medicine and surgery2022

Chunjuan Jiang, Liwei Zhao, Bowen Xin, Guang Ma, Xiuying Wang, Shaoli Song

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. BMC cancer · 2025
    Article
  6. Quantitative imaging in medicine and surgery · 2025
    Article
  7. Article
  8. Review
  9. Clinical application ofJapanese journal of radiology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The application ofQuantitative imaging in medicine and surgery · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Quantitative imaging in medicine and surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Chunjuan Jiang *Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Liwei Zhao *School of Computer Science, The University of Sydney, Sydney, NSW, Australia.
Bowen XinSchool of Computer Science, The University of Sydney, Sydney, NSW, Australia.
Guang MaDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Xiuying WangSchool of Computer Science, The University of Sydney, Sydney, NSW, Australia.
Shaoli SongDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.
Fudan University Shanghai Cancer Center · CNUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Microvascular invasion (MVI) is a critical risk factor for early recurrence of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). The aim of this study was to explore the contribution of Methods: In this retrospective study, 127 (HCC: ICC =76:51) patients with suspected MVI accompanied by either HCC or ICC were included (In HCC group, MVI positive: negative =46:30 in ICC group, MVI positive: negative =31:20). Results-driven feature engineering workflow was used to select the most predictive feature combinations. The prediction model was based on supervised machine learning classifier. Ten-fold cross validation on training cohort and independent test cohort were constructed to ensure stability and generalization ability of models. Results: For HCC and ICC classification, radiomics predictors composed of two PET and one CT feature achieved area under the curve (AUC) of 0.86 (accuracy, sensitivity, specificity was 0.82, 0.78, 0.88, respectively) on test cohort. For MVI prediction, in HCC group, our MVI prediction model achieved AUC of 0.88 (accuracy, sensitivity, specificity was 0.78, 0.88, 0.60 respectively) with three PET features associated with tumor stage on test cohort. In ICC group, the phenotype composed of two PET features and carbohydrate antigen 19-9 (CA19-9) achieved AUC of 0.90 (accuracy, sensitivity, specificity was 0.77, 0.75, 0.80, respectively). Conclusions:

Indexed as

18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT)hepatocellular carcinoma (HCC)intrahepatic cholangiocarcinoma (ICC)microvascular invasion (MVI)radiomics

Identifiers

PMID35919043
PMCPMC9338369
OpenAlexW4285289385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.