Evidence map›Paper›PMID 35918988›Full record

ArticleIndian journal of ophthalmology2022

Keratoplasty rejection after messenger RNA vaccine (BNT162b2) for COVID-19.

Maria Eduarda Andrade E Andrade, Juliane Cardoso Rodrigues, Elvio Ferreira Junior, Mario Henrique Camargos de Lima

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. COVID-19 vaccination and corneal allograft rejection- a review.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Eduarda Andrade E AndradeClínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, São Paulo, Brazil.
Juliane Cardoso RodriguesClínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, São Paulo, Brazil.
Elvio Ferreira JuniorClínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, São Paulo, Brazil.
Mario Henrique Camargos de LimaClínica Oftalmológica do Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report shows a case of corneal transplant rejection after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), short after receiving the BNT162b2 vaccine, in a patient who had undergone keratoplasty more than 20 years ago, with no previous episodes of rejection and no other factor that could lead to the findings on his examinations. After treatment with high doses of topic, oral, and sub-conjunctival corticoids, the patient had a favorable therapeutic response. The signs of corneal transplant rejection must be oriented to the patients and the causing factors actively searched by ophthalmologists so that treatment is rapidly initiated and sequels are avoided. This report raises the question if these events are correlated and whether the patient should receive the second dose of the vaccine against SARS-CoV-2 or not.

Indexed as

BNT162 VaccineCorneal TransplantationCOVID-19Graft RejectionHumansSARS-CoV-2BNT162 VaccineBNT162b2 vaccinecoronaviruskeratoplastypenetratingvaccine

Identifiers

PMID35918988
PMCPMC9672786
OpenAlexW4289783289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.