Evidence map›Paper›PMID 35918837›Full record

ArticleJournal of obesity & metabolic syndrome2022

Increased Body Mass Index and Metabolic Syndrome Are Associated with Poor Outcomes in SARS-CoV-2-Positive Emergency Department Patients.

Joby J Thoppil, Lauren K Stewart, Leland Pung, Kristen E Nordenholz, Carlos A Camargo, D Mark Courtney, Jeffrey A Kline, RECOVER Network

Open access · diamondAbstract read
In one paragraph

Article in Journal of obesity & metabolic syndrome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. COVID-19, Obesity, and GRP78: Unraveling the Pathological Link.Journal of obesity & metabolic syndrome · 2023
    Review
  6. Article
  7. Does Obesity Paradox Exist in COVID-19 Mortality?Journal of obesity & metabolic syndrome · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Joby J ThoppilDepartment of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Lauren K StewartDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Leland PungDuke University School of Medicine, Duke University, Durham, NC, USA.
Kristen E NordenholzDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
D Mark CourtneyDepartment of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Jeffrey A KlineDepartment of Emergency Medicine, Wayne State University, Detroit, MI, USA.ORCID https://orcid.org/0000-0001-7190-3109
RECOVER Network
The University of Texas Southwestern Medical Center · USDuke University · USHarvard University · USIndiana University School of MedicineUniversity of Colorado Denver · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Increased body mass index (BMI) and metabolic syndrome (MetS) have been associated with adverse outcomes in viral syndromes. We sought to examine associations of increased BMI and MetS on several clinical outcomes in patients tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods: The registry of suspected COVID-19 in emergency care (RECOVER) is an observational study of SARS-CoV-2-tested patients (n=27,051) across 155 United States emergency departments (EDs). We used multivariable logistic regression to test for associations of several predictor variables with various clinical outcomes. Results: We found that a BMI ≥30 kg/m Conclusion: In this large nationwide sample of ED patients, we report a significant association of both high BMI and composite MetS with poor outcomes in SARS-CoV-2-positive patients. Findings suggest that composite MetS profile may be a more universal predictor of adverse disease outcomes, while the impact of BMI is more heavily modulated by SARS-CoV-2 status.

Indexed as

Body mass indexCOVID-19Metabolic syndromeObesitySARS-CoV-2

Identifiers

PMID35918837
PMCPMC9579471
OpenAlexW4289786931

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.