Evidence map›Paper›PMID 35918738›Full record

ArticleImplementation science communications2022

Integrating ART adherence support technologies in the care of pregnant and postpartum people with HIV: a qualitative study.

Sara Rendell, Harald Schmidt, Rebecca Neergaard, Hervette Nkwihoreze, Zoe Barbati, William R Short, Aadia I Rana, Anandi N Sheth, Rachel K Scott, Sonia Sethi and 1 more

Abstract read
In one paragraph

Article in Implementation science communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara RendellPerelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA. srendell@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0002-8201-4793
Harald SchmidtDepartment of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Rebecca NeergaardDepartment of Family Medicine and Community Health, Perelman School of Medicine, Philadelphia, PA, USA.
Hervette NkwihorezeDepartment of Medicine, Division of Infectious Diseases, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Zoe BarbatiDepartment of Family Medicine and Community Health, Perelman School of Medicine, Philadelphia, PA, USA.
William R ShortDepartment of Medicine, Division of Infectious Diseases, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Aadia I RanaDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Anandi N ShethInfectious Diseases Program, Grady Health System, Atlanta, GA, USA.
Rachel K ScottMedStar Health Research Institute and Washington Hospital Center, Washington, DC, USA.
Sonia SethiDepartment of Medicine, Rush University Medical Center, Chicago, IL, USA.
Florence M MomplaisirLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ronald G Collman · 1999 to 2026
$78.6M
A Randomized Controlled Trial of Women Involved in Supporting Health (WISH), a Peer-Led Intervention to Improve Postpartum Retention in HIV CareR01MD013558 · NIMHD · UNIVERSITY OF PENNSYLVANIA · PI MOMPLAISIR, FLORENCE M · 2018 to 2022
$2.9M
NIAID NIH HHS P30 AI045008NIMHD NIH HHS R01 MD013558NIMHD NIH HHS R01MD013558-02S1
6 · The paper itself

Abstract

backgroundWe have a limited understanding on how to best integrate technologies to support antiretroviral therapy (ART) adherence in routine HIV care.

methodsWe conducted semi-structured interviews with multidisciplinary providers caring for pregnant and postpartum people with HIV and asked providers about their perspectives on utilizing adherence support technologies such as text messages, video check-ins with providers or automated with facial recognition for directly-observed-therapy, signaling pill bottle, and signaling pill to support ART adherence. Each approach generated an adherence report. The interview instrument was guided by the Consolidated Framework for Implementation Research and included questions on the implementation climate, barriers, and facilitators to the clinical integration of the adherence approach and strategies that could be used to maximize this integration. The order of adherence support technologies was randomized to minimize bias. We used a modified grounded theory to develop the coding structure and two coders applied the codebook to the transcripts after establishing strong inter-rater reliability with 20% of interviews (kappa = 0.82).

resultsBetween March and December 2020, we conducted 26 in-depth, semi-structured interviews with providers who weighed several factors when considering each approach, including the approach's effect on patient-provider interaction in and outside of the clinic visit, timing for and duration of the approach's utility, threat of disclosing status, and added burden to providers (e.g., needing to act on generated information) or to patients (e.g., needing to hide the signaling pills, responding to text messages). Providers' most preferred approach was text-messages, and the least preferred was the signaling pill. Barriers to acceptability varied by approach and included perceived surveillance, violation of privacy, added time demand for providers, potential inaccuracy of the adherence data generated, and negative impact on the patient-provider relationship, particularly if the approach was perceived as coercive. Payers anticipated regulatory hurdles with unfamiliar approaches, particularly the signaling pill and signaling pill bottle. Facilitators included strengthened therapeutic alliance, predictable reminder mechanisms, and options for customization according to patient preference.

conclusionsOur study elucidates barriers and facilitators to integrating technology-based adherence support approaches in clinical care to support adherence of pregnant and postpartum people with HIV.

Indexed as

AdherenceAnti-retroviral agents (ARV)HIV care continuumImplementation sciencePostpartum periodPregnancy

Identifiers

PMID35918738
PMCPMC9344442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.