Evidence map›Paper›PMID 35918691›Full record

ArticleLipids in health and disease2022

Association of lipid profile with obesity among breast cancer survivors: a cross-sectional study.

Akinkunmi Paul Okekunle, Ga-Eun Yie, Sihan Song, Zisun Kim, Hyun Jo Youn, Jihyoung Cho, Jun Won Min, Yoo Seok Kim, Jung Eun Lee

Abstract read
In one paragraph

Article in Lipids in health and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akinkunmi Paul OkekunleDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.ORCID http://orcid.org/0000-0003-4825-4934
Ga-Eun YieDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
Sihan SongDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea.
Zisun KimDepartment of Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, 14584, Korea.
Hyun Jo YounDepartment of Surgery, Jeonbuk National University Medical School, Jeonju, 54907, Korea.
Jihyoung ChoDepartment of Surgery, Keimyung University School of Medicine, Daegu, 42601, Korea.
Jun Won MinDepartment of Surgery, Dankook University Hospital, Dankook University College of Medicine, Cheonan, 31116, Korea.
Yoo Seok KimDepartment of Surgery, Chosun University Hospital, Chosun University College of Medicine, Gwangju, 61453, Korea.
Jung Eun LeeDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea. jungelee@snu.ac.kr.

Funding

National Research Foundation of Korea 2020H1D3A1A04081265
6 · The paper itself

Abstract

backgroundThe role of lipid metabolism in obesity and cancer manifestations cannot be underestimated, but whether alterations in lipid metabolism can manipulate the vasculature to promote obesity among breast cancer (BC) survivors is yet to be clearly understood. This study quantified plasma lipid and particle sizes using high-throughput proton (

methodsA total of 348 (225 premenopausal and 123 postmenopausal) BC survivors enrolled from five hospitals in Korea were included. We assessed thirty-four plasma lipid biomarkers using

resultsMean (SD) values of BMI was 23.3 (3.2) kg/m

conclusionsIncreasing levels of plasma total TG and TG in lipoproteins were associated with increasing levels of BMI among premenopausal BC survivors. High HDL-C levels and large HDL-p were inversely associated with obesity among premenopausal BC survivors. Due to the cross-sectional design of this study, longitudinal studies are necessary to examine the association between obesity and lipid profile among BC survivors.

Indexed as

Breast NeoplasmsCancer SurvivorsBody Mass IndexCholesterol, HDLCross-Sectional StudiesFemaleHumansLipoproteinsLipoproteins, LDLObesityTriglyceridesCholesterol, HDLLipoproteinsLipoproteins, LDLTriglycerides1H proton NMRBreast cancerLipidsMenopauseMetabolomicsObesity

Identifiers

PMID35918691
PMCPMC9344652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.