ArticleBMC psychiatry2022
Antepartum sleep quality, mental status, and postpartum depressive symptoms: a mediation analysis.
Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 20 citations in OpenAlex.
- Association of inflammatory biomarkers during pregnancy and the postpartum period with the risk of postpartum anxiety symptoms.Brain, behavior, & immunity - health · 2026Article
- Development trajectories of marital satisfaction and postpartum depression: a longitudinal study.Frontiers in medicine · 2026Article
- Sleep Quality and Depressive Symptoms Among Pregnant Women in the Third Trimester: A Cross-Sectional Latent Profile and Network Analysis.International journal of women's health · 2026Article
- Prevalence and risk factors of postpartum depression, anxiety, and comorbidity of both disorders: a cross-sectional study.BMC pregnancy and childbirth · 2025Article
- [Latent profile analysis of psychological capital and antenatal depression among pregnant women].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Association between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety.BMC pregnancy and childbirth · 2025Article
- Effects of psychosocial factors on postpartum depression: a half-longitudinal mediation analysis of cognitive reactivity.BMC pregnancy and childbirth · 2025Article
- Associations between physical activity and prenatal depression and anxiety symptoms: a cross-sectional study.Frontiers in public health · 2025Article
- Prevalence and Factors Associated With Antepartum Depression Among Pregnant Women in Latent Labor: A Multi-Facility Cross-Sectional Study in Rural Southwestern Uganda.International journal of women's health · 2025Article
- Evaluation of depression at 6 and 12 months postpartum by examining depressive symptoms and self-harm ideation during the early postpartum period: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.PCN reports : psychiatry and clinical neurosciences · 2024Article
- Domestic Violence Experience, Past Depressive Disorder, Unplanned Pregnancy, and Suicide Risk in the First Year Postpartum: Mediating Effect of Postpartum Depression.Psychiatry investigation · 2024Article
- Influencing factors of sleep quality in pregnant: a structural equation model approach.BMC psychology · 2024Article
- Prevalence and Influencing Factors of Severe Depression in Nurses During and After the COVID-19 Pandemic: A Large-Scale Multicenter Study.Depression and anxiety · 2024Observational
- Risk factors for the development of postpartum depression in individuals who screened positive for antenatal depression.BMC psychiatry · 2023Article
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Authors and funding
17 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPoor sleep quality and maternal mood disturbances are common during pregnancy and may play pivotal roles in the development of postpartum depression. We aim to examine the trajectories of sleep quality and mental health in women from early pregnancy to delivery and explore the mediating effects of sleep quality and mental status on the link between antepartum depressive symptoms and postpartum depressive symptoms.
methodsIn an ongoing prospective birth cohort, 1301 women completed questionnaires in the first, second and third trimesters and at 6 weeks postpartum. In each trimester, sleep quality was measured utilizing the Pittsburgh Sleep Quality Index (PSQI), and mental health was assessed with the Center for Epidemiologic Studies Depression Scale (CES-D), the Self-Rating Anxiety Scale (SAS) and the Perceived Stress Scale (PSS). Postpartum depressive symptoms were evaluated by the Edinburgh Postnatal Depression Scale (EPDS). The bootstrap method was used to test the mediation effect.
resultsThe PSQI, CES-D, and SAS scores presented U-shaped curves across the antenatal period while the PSS score followed a descending trend. Antenatal sleep quality, depressive symptoms, anxiety symptoms and perceived stress all predicted depressive symptoms at 6 weeks postpartum. The influence of antepartum depressive symptoms on postpartum depressive symptoms was mediated by antepartum sleep quality and anxiety symptoms, which accounted for 32.14%, 39.25% and 31.25% in the first, second and third trimesters (P = 0.002, P = 0.001, P = 0.001, respectively).
conclusionsPoor sleep quality and anxiety symptoms in pregnancy mediated the relationship between antepartum depressive symptoms and postpartum depressive symptoms. Interventions aimed at detecting and managing sleep quality and elevated anxiety among depressed women in pregnancy warrant further investigation as preventative strategies for postpartum depression.
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