ArticleNature microbiology2022
Trafficked Malayan pangolins contain viral pathogens of humans.
Article in Nature microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Systematic review and integrated data analysis reveal diverse pangolin-associated microbes with infection potential.Nature communications · 2023Pooled it
- Differences in Oropharyngeal Viromes Between Surviving and Deceased Malayan Pangolins in a Rescue Context.Microorganisms · 2026Article
- Genetic diversity of pangolin coronaviruses reveals a key immuno-evasive substitution at spike residue 519.Journal of virology · 2026Article
- Addressing the zoonotic threat of merbecoviruses.Nature microbiology · 2026Review
- Age-dependent expression and antiviral activity of interferon epsilon in respiratory epithelium.Journal of virology · 2026Article
- Virome diversity, evolution, transmission networks, and zoonotic potential of wildlife on the Qinghai-Tibet plateau.NPJ biofilms and microbiomes · 2026Article
- A Unified Framework to Prioritize RNA Virus Cross-Species Transmission Risk Across an Expansive Host Landscape.Viruses · 2026Article
- Multiple etiological agents associated with the deaths of trafficked pangolins.Zoological research · 2026Article
- Biodiversity and emerging infectious threats: the microbial dark matter of Southwest China.Frontiers in microbiology · 2026Review
- Article
- Diverse virome and potential pathogens in five tick species from metropolis surroundings of Beijing and Tianjin, China.NPJ biofilms and microbiomes · 2025Article
- A tombus-like virus in patients with lower respiratory tract infection: an observational study based on meta-transcriptomic sequencing.Emerging microbes & infections · 2025Observational
- SegFinder: an automated tool for identifying complete RNA virus genome segments through co-occurrence in multiple sequenced samples.Briefings in bioinformatics · 2025Article
- Towards tick virome and emerging tick-borne viruses: Protocols, challenges and perspectives.iMetaOmics · 2025Article
- Article
- Small mammals and associated infections in China: a systematic review and spatial modelling analysis.The Lancet regional health. Western Pacific · 2025Article
- Identification and phylogenetic characterization of novel hunnivirus recombinant strains in cattle from Guangxi, China.Frontiers in cellular and infection microbiology · 2025Article
- Evidences from gut microbiome and habitat landscape indicate continued threat of extinction for the Hainan gibbon.iScience · 2024Article
- Binding affinity between coronavirus spike protein and human ACE2 receptor.Computational and structural biotechnology journal · 2024Review
- Serological evidence of sarbecovirus exposure along Sunda pangolin trafficking pathways.BMC biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pangolins are the most trafficked wild animal in the world according to the World Wildlife Fund. The discovery of SARS-CoV-2-related coronaviruses in Malayan pangolins has piqued interest in the viromes of these wild, scaly-skinned mammals. We sequenced the viromes of 161 pangolins that were smuggled into China and assembled 28 vertebrate-associated viruses, 21 of which have not been previously reported in vertebrates. We named 16 members of Hunnivirus, Pestivirus and Copiparvovirus pangolin-associated viruses. We report that the L-protein has been lost from all hunniviruses identified in pangolins. Sequences of four human-associated viruses were detected in pangolin viromes, including respiratory syncytial virus, Orthopneumovirus, Rotavirus A and Mammalian orthoreovirus. The genomic sequences of five mammal-associated and three tick-associated viruses were also present. Notably, a coronavirus related to HKU4-CoV, which was originally found in bats, was identified. The presence of these viruses in smuggled pangolins identifies these mammals as a potential source of emergent pathogenic viruses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.