Evidence map›Paper›PMID 35918071›Full record

SynthesisBMJ global health2022

Racial discrimination and adverse pregnancy outcomes: a systematic review and meta-analysis.

Kim Robin van Daalen, Jeenan Kaiser, Samuel Kebede, Gabriela Cipriano, Hassan Maimouni, Ekiomoado Olumese, Anthea Chui, Isla Kuhn, Clare Oliver-Williams

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ global health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Interventions to Address Disparities in Perinatal Outcomes by Ethnicity: A Systematic Review.BJOG : an international journal of obstetrics and gynaecology · 2025
    Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Experiences of Discrimination and DNA Methylation Among Black Nulliparous Women.Journal of racial and ethnic health disparities · 2026
    Article
  11. A Qualitative Study of the Impact of Police Violence on Black Birthing People.Journal of racial and ethnic health disparities · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kim Robin van DaalenCardiovascular Epidemiology Unit, Department of Public Health and Primary Care, Cambridge University, Cambridge, UK krv22@cam.ac.uk.ORCID 0000-0001-6955-9708
Jeenan KaiserFaculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Samuel KebedeDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York City, USA.
Gabriela CiprianoCayetano Heredia University, Lima, Peru.
Hassan MaimouniUniversity of East Anglia, Norwich, UK.
Ekiomoado OlumeseVanderbilt University School of Medicine, Nashville, Tennessee, USA.
Anthea ChuiSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.
Isla KuhnMedical Library, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Clare Oliver-WilliamsCardiovascular Epidemiology Unit, Department of Public Health and Primary Care, Cambridge University, Cambridge, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRacial discrimination has been consistently linked to various health outcomes and health disparities, including studies associating racial discrimination with patterns of racial disparities in adverse pregnancy outcomes. To expand our knowledge, this systematic review and meta-analysis assesses all available evidence on the association between self-reported racial discrimination and adverse pregnancy outcomes.

methodsEight electronic databases were searched without language or time restrictions, through January 2022. Data were extracted using a pre-piloted extraction tool. Quality assessment was conducted using the Newcastle-Ottawa Scale (NOS), and across all included studies using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Random effects meta-analyses were performed on preterm birth and small for gestational age. Heterogenicity was assessed using Cochran's χ

resultsOf 13 597 retrieved records, 24 articles were included. Studies included cohort, case-control and cross-sectional designs and were predominantly conducted in the USA (n=20). Across all outcomes, significant positive associations (between experiencing racial discrimination and an adverse pregnancy event) and non-significant associations (trending towards positive) were reported, with no studies reporting significant negative associations. The overall pooled odds ratio (OR) for preterm birth was 1.40 (95% CI 1.17 to 1.68; 13 studies) and for small for gestational age it was 1.23 (95% CI 0.76 to 1.99; 3 studies). When excluding low-quality studies, the preterm birth OR attenuated to 1.31 (95% CI 1.08 to 1.59; 10 studies). Similar results were obtained across sensitivity and subgroup analyses, indicating a significant positive association.

conclusionThese results suggest that racial discrimination has adverse impacts on pregnancy outcomes. This is supported by the broader literature on racial discrimination as a risk factor for adverse health outcomes. To further explore this association and underlying mechanisms, including mediating and moderating factors, higher quality evidence from large ethnographically diverse cohorts is needed.

Indexed as

Premature BirthRacismCohort StudiesCross-Sectional StudiesFemaleHumansInfant, NewbornPregnancyPregnancy Outcomechild healthmaternal healthpublic healthsystematic review

Identifiers

PMID35918071
PMCPMC9344988

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.