Evidence map›Paper›PMID 35917762›Full record

ArticleDrug and alcohol dependence2022

The role of mood disorders in the progression of and recovery from alcohol and drug use problems: A latent transition analysis.

Rosa M Crum, Kerry M Green, Masoumeh Amin-Esmaeili, Ryoko Susukida, Ramin Mojtabai, Carla L Storr, Kira E Riehm, Andrea S Young, Beth A Reboussin

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In one paragraph

Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Rosa M CrumDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: rcrum1@jhu.edu.
Kerry M GreenDepartment of Behavioral and Community Health, University of Maryland College Park School of Public Health, College Park, MD, USA.
Masoumeh Amin-EsmaeiliDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ryoko SusukidaDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ramin MojtabaiDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Carla L StorrDepartment of Family and Community Health, University of Maryland School of Nursing, Baltimore, MD, USA.
Kira E RiehmDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Andrea S YoungDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Beth A ReboussinDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Funding

RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
Comorbid Patterns with Alcohol Use DisordersR01AA016346 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CRUM, ROSA M. · 2009 to 2019
$2.8M
Preventive Effects of Treatment for Childhood Mental Illness on Adolescent Substance UseK23DA044288 · NIDA · JOHNS HOPKINS UNIVERSITY · PI YOUNG, ANDREA S · 2018 to 2022
$784k
NIAAA NIH HHS R01 AA016346NIDA NIH HHS K23 DA044288NIMH NIH HHS T32 MH013043
6 · The paper itself

Abstract

introductionLongitudinal research assessing whether mood disorders predict substance use behaviors is limited. We extend our prior work evaluating transition patterns with alcohol use to assess patterns with alcohol and drug use problems.

methodUsing National Epidemiologic Survey on Alcohol and Related Conditions prospective data, waves 1 and 2, we completed latent class analyses to empirically define classes of alcohol and drug problems from DSM disorder criteria. Latent transition analyses were used to assess associations of lifetime mood disorders at baseline with transitions across classes of alcohol and drug problems during follow-up.

resultsA three-class model of alcohol and drug problems was identified (No problems, Alcohol Problems Only, and Alcohol and Drug Problems) for males and females. Females with mood disorders were over two times more likely to transition from No Problems, and Alcohol Problems Only at baseline to having both Alcohol and Drug Problems at follow-up relative to those without mood disorders (aOR=2.30, 95 % CI=1.31-4.05, p = 0.004, and aOR=2.64, CI=1.24-5.62, p = 0.011, respectively). Furthermore, females with mood disorders were significantly less likely to recover from baseline Alcohol and Drug Problems to Alcohol Problems Only at follow-up (aOR=0.35, CI=0.12-0.98, p = 0.047) relative to those without mood disorders. There were no significant findings for males. DISCUSSION: Our study provides evidence that mood disorders impact transitions through classes of alcohol and drug problems among females. The findings emphasize the need for ongoing evaluation of substance use among those with mood conditions, and recognition and treatment of mood disorders among those recovering from substance use problems.

Indexed as

Alcohol-Related DisordersSubstance-Related DisordersAlcohol DrinkingFemaleHumansMaleMood DisordersProspective StudiesAbuseAlcoholDependenceDepressionDrug useLatent class analysisLatent transition analysisMood disordersSubstance use

Identifiers

PMID35917762
PMCPMC10187057

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.