Evidence map›Paper›PMID 35917480›Full record

ArticleJCO clinical cancer informatics2022

Assessment of Electronic Health Record for Cancer Research and Patient Care Through a Scoping Review of Cancer Natural Language Processing.

Liwei Wang, Sunyang Fu, Andrew Wen, Xiaoyang Ruan, Huan He, Sijia Liu, Sungrim Moon, Michelle Mai, Irbaz B Riaz, Nan Wang and 4 more

Abstract readScoping Review
In one paragraph

Article in JCO clinical cancer informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  4. Using large language models to identify prediagnostic clinical features of ovarian cancer from healthcare records: a population-based case-control study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Liwei WangDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.ORCID 0000-0001-9970-8604
Sunyang FuDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.ORCID 0000-0003-1691-5179
Andrew WenDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.ORCID 0000-0001-9090-8028
Xiaoyang RuanDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.
Huan HeDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.ORCID 0000-0003-1312-4195
Sijia LiuDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.ORCID 0000-0001-9763-1164
Sungrim MoonDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.ORCID 0000-0002-9191-3897
Michelle MaiDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.
Irbaz B RiazDepartment of Hematology/Oncology, Mayo Clinic, Scottsdale, AZ.ORCID 0000-0003-4249-0311
Nan WangDepartment of Computer Science and Engineering, College of Science and Engineering, University of Minnesota, Minneapolis, MN.
Ping YangDepartment of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ.ORCID 0000-0002-8588-847X
Hua XuSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX.
Jeremy L WarnerDepartments of Medicine (Hematology/Oncology), Vanderbilt University, Nashville, TN.ORCID 0000-0002-2851-7242
Hongfang LiuDepartment of Artificial Intelligence and Informatics, Mayo Clinic, Rochester, MN.ORCID 0000-0003-2570-3741

Funding

Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
Advancing Cancer Pharmacoepidemiology Research Through EHRs and InformaticsU24CA194215 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAO, CUI, YANG, PING · 2016 to 2020
$3.3M
NCATS NIH HHS U01 TR002062NCI NIH HHS U24 CA194215
6 · The paper itself

Abstract

purposeThe advancement of natural language processing (NLP) has promoted the use of detailed textual data in electronic health records (EHRs) to support cancer research and to facilitate patient care. In this review, we aim to assess EHR for cancer research and patient care by using the Minimal Common Oncology Data Elements (mCODE), which is a community-driven effort to define a minimal set of data elements for cancer research and practice. Specifically, we aim to assess the alignment of NLP-extracted data elements with mCODE and review existing NLP methodologies for extracting said data elements.

methodsPublished literature studies were searched to retrieve cancer-related NLP articles that were written in English and published between January 2010 and September 2020 from main literature databases. After the retrieval, articles with EHRs as the data source were manually identified. A charting form was developed for relevant study analysis and used to categorize data including four main topics: metadata, EHR data and targeted cancer types, NLP methodology, and oncology data elements and standards.

resultsA total of 123 publications were selected finally and included in our analysis. We found that cancer research and patient care require some data elements beyond mCODE as expected. Transparency and reproductivity are not sufficient in NLP methods, and inconsistency in NLP evaluation exists.

conclusionWe conducted a comprehensive review of cancer NLP for research and patient care using EHRs data. Issues and barriers for wide adoption of cancer NLP were identified and discussed.

Indexed as

Natural Language ProcessingNeoplasmsElectronic Health RecordsHumansInformation Storage and RetrievalPatient Care

Identifiers

PMID35917480
PMCPMC9470142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.