Evidence map›Paper›PMID 35917457›Full record

ArticleBlood advances2023

Interferon-γ blockade in CAR T-cell therapy-associated macrophage activation syndrome/hemophagocytic lymphohistiocytosis.

Michael Rainone, Dat Ngo, John H Baird, L Elizabeth Budde, Myo Htut, Ibrahim Aldoss, Vinod Pullarkat

Abstract read
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael RainoneDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.
Dat NgoDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.
John H BairdDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.ORCID 0000-0001-8291-6546
L Elizabeth BuddeDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.ORCID 0000-0003-1464-5494
Myo HtutDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.
Ibrahim AldossDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.
Vinod PullarkatDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.ORCID 0000-0001-9129-3424

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lymphohistiocytosis, HemophagocyticMacrophage Activation SyndromeHumansImmunotherapy, AdoptiveInterferon-gammaInterferon-gamma

Identifiers

PMID35917457
PMCPMC9979758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.