ArticleJournal of ultrasound2023
Ophthalmic artery Doppler for pre-eclampsia prediction at the first trimester: a Bayesian survival-time model.
Article in Journal of ultrasound, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- First-trimester ophthalmic artery Doppler for prediction of early-onset and preterm preeclampsia: a systematic review and critical appraisal.BMC pregnancy and childbirth · 2026Pooled it
- Ophthalmic artery Doppler measurements in Chinese women with healthy pregnancies.BMC pregnancy and childbirth · 2026Article
- The Role of Ophthalmic Artery Doppler in Predicting Preeclampsia: A Review of the Literature.Medicina (Kaunas, Lithuania) · 2026Review
- Reference ranges for peak systolic velocity ratio of ophthalmic artery Doppler from first to third trimester based on serial Doppler measurements.Archives of gynecology and obstetrics · 2025Article
- Comparison of first trimester preeclampsia combined screening performances with various approaches in the Indonesian population.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Maternal Ophthalmic Artery Resistance in Pregnancies With Pre-Eclampsia Compared to Normotensive Participants.Australasian journal of ultrasound in medicine · 2025Article
- Ophthalmic Artery Doppler Indices at 11-13 Weeks of Gestation in Relation to Early and Late Preeclampsia.Journal of clinical medicine · 2025Article
- Preliminary exploration of prediction model and nomograph drawing of Doppler peak systolic velocity ratio, peak systolic velocity 1 and peak systolic velocity 2 of ophthalmic artery in pregnant women for small for gestational age infants.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo develop a Bayesian survival-time model for the prediction of pre-eclampsia (PE) at the first trimester using a combination of established biomarkers including maternal characteristics and history, mean arterial pressure (MAP), uterine artery Doppler pulsatility index (UtA-PI), and Placental Growth Factor (PlGF)) with an ophthalmic artery Doppler peak ratio (PR) analysis.
methodsThe receiving operator curve (ROC) analysis was used to determine the area under the curve (AUC), detection rate (DR), and positive screening cut-off value of the model in predicting the occurrence of early-onset PE (< 34 weeks' gestation) and preterm PE (< 37 weeks' gestation).
resultsOf the 946 eligible participants, 71 (7.49%) subjects were affected by PE. The incidences of early-onset and preterm PE were 1% and 2.2%, respectively. At a 10% false-positive rate, using the high-risk cut-off 1:49, with AUC 0.981 and 95%CI 0.965-0.998, this model had an 100% of DR in predicting early-onset PE. The DR of this model in predicting preterm PE is 71% when using 1:13 as the cut-off, with AUC 0.919 and 95%CI 0.875-0.963.
conclusionCombination ophthalmic artery Doppler PR with the previously established biomarkers could improve the accuracy of early and preterm PE prediction at the first trimester screening.
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