Evidence map›Paper›PMID 35916621›Full record

ReviewThe journal of trauma and acute care surgery2023

Time is tissue: Barriers to timely transfusion after pediatric injury.

Travis M Sullivan, Waverly V Gestrich-Thompson, Zachary P Milestone, Randall S Burd

Abstract readReview
In one paragraph

Review in The journal of trauma and acute care surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Travis M SullivanFrom the Division of Trauma and Burn Surgery, Children's National Hospital, Washington, DC.
Waverly V Gestrich-Thompson
Zachary P Milestone
Randall S Burd

Funding

Intention-aware Recommender System for Improving Trauma Resuscitation OutcomesR01LM011834 · NLM · CHILDREN'S RESEARCH INSTITUTE · PI BURD, RANDALL S., MARSIC, IVAN · 2014 to 2023
$4.7M
NLM NIH HHS R01 LM011834
6 · The paper itself

Abstract

abstractStrategies to improve outcomes among children and adolescents in hemorrhagic shock have primarily focused on component resuscitation, pharmaceutical coagulation adjuncts, and hemorrhage control techniques. Many of these strategies have been associated with better outcomes in children, but the barriers to their use and the impact of timely use on morbidity and mortality have received little attention. Because transfusion is uncommon in injured children, few studies have identified and described barriers to the processes of using these interventions in bleeding patients, processes that move from the decision to transfuse, to obtaining the necessary blood products and adjuncts, and to delivering them to the patient. In this review, we identify and describe the steps needed to ensure timely blood transfusion and propose practices to minimize barriers in this process. Given the potential impact of time on hemorrhage associated outcomes, ensuring timely intervention may have a similar or greater impact than the interventions themselves.

Indexed as

Shock, HemorrhagicWounds and InjuriesAdolescentBlood CoagulationBlood TransfusionChildHemorrhageHumansResuscitation

Identifiers

PMID35916621
PMCPMC9805480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.