ArticleACS nano2022
Platelet-Inspired Intravenous Nanomedicine for Injury-Targeted Direct Delivery of Thrombin to Augment Hemostasis in Coagulopathies.
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Article in ACS nano, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
What it found
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Procoagulant platelets: linking coagulation and thromboinflammation in cardiovascular disease.Nature reviews. Cardiology · 2026Review
- Advances in hemostatic biomaterials: biomimetic strategies, nanotechnology, and smart therapeutics.Burns & trauma · 2026Review
- Engineering design of platelet-mimicking therapeutic systems: multilevel biomimicry, gating strategies, and translational boundaries.Frontiers in bioengineering and biotechnology · 2026Review
- Total thrombus formation system exploration of primary hemostasis in cirrhotic patients.Research and practice in thrombosis and haemostasis · 2026Article
- In Situ Crosslinking of Bioorthogonal Nanoparticles to Restore Clot Stability in Coagulopathic Blood.Bio-protocol · 2025Article
- Biosynthetic blood surrogates: Current status and future opportunities.Bioengineering & translational medicine · 2025Review
- Platelet-derived biomimetic nanoplatforms: a promising drug delivery strategy for cardiovascular disease.Journal of nanobiotechnology · 2025Review
- Bioactive hemostatic materials: a new strategy for promoting wound healing and tissue regeneration.MedComm · 2025Review
- OPSALC: On-Particle Solvent-Assisted Lipid Coating to Create Erythrocyte Membrane-like Coatings with Improved Hemocompatibility.ACS applied materials & interfaces · 2025Article
- Emulsion-Based Encapsulation of Fibrinogen with Calcium Carbonate for Hemorrhage Control.Journal of functional biomaterials · 2025Article
- Transfusion biomaterials for hemostasis.Journal of thrombosis and haemostasis : JTH · 2025Review
- Article
- Highly efficient photoelectrochemical aptasensor based on CdS/CdTe QDs co-sensitized TiOMikrochimica acta · 2024Article
- Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia.Iranian journal of basic medical sciences · 2024Article
- Multiscale physics-basedFrontiers in drug delivery · 2024Review
- ENGINEERED INTRAVENOUS THERAPIES FOR TRAUMA.Current opinion in biomedical engineering · 2023Article
- Nanoparticles-induced potential toxicity on human health: Applications, toxicity mechanisms, and evaluation models.MedComm · 2023Review
- Engineering a Two-Component Hemostat for the Treatment of Internal Bleeding through Wound-Targeted Crosslinking.Advanced healthcare materials · 2023Article
- Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models.Blood · 2023Article
- Design of biopolymer-based hemostatic material: Starting from molecular structures and forms.Materials today. Bio · 2022Review
Corrections and comments
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Authors and funding
21 authors at 2 institutions in 1 country.
Aditya GirishDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Ketan JollyDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Nijmeh AlsaadiDepartment of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15123, United States.
Maria de la FuenteDepartment of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Arielle RecchioneDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Ran AnDepartment of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Dante DisharoonDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Zachary SecundaDepartment of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15123, United States.
Shruti RaghunathanDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Norman F LucDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Cian DesaiDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Elizabeth KnaussDepartment of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Xu HanDepartment of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Keren HuDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Hanyang WangDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Ujjal Didar Singh SekhonDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Nathan RohnerDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Umut A GurkanDepartment of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Marvin NiemanDepartment of Pharmacology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Matthew D NealDepartment of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15123, United States.ORCID 0000-0001-8931-6236
Anirban Sen GuptaDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.ORCID 0000-0002-5773-0667
Case Western Reserve University · USUniversity of Pittsburgh · US
Funding
The role of protease activated receptors on platelets.R01HL098217 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI NIEMAN, MARVIN THOMAS · 2010 to 2024
$4.6MPREDOCTORAL TRAINING PROGRAM IN MOLECULAR THERAPEUTICST32GM008803 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI MIEYAL, JOHN J, NIEMAN, MARVIN THOMAS · 2001 to 2023
$4.2MHeteromutivalent Peptide-Lipid Nanoconstructs as Artificial Platelet AnaloguesR01HL121212 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI SEN GUPTA, ANIRBAN · 2014 to 2024
$4.1MMechanistic Elucidation and Targeted Therapy of Platelet Dysfunction After TraumaR35GM119526 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEAL, MATTHEW D · 2016 to 2025
$3.9MMechanisms of platelet exosome-mediated acute chest syndrome in sickle cell diseaseR01HL141080 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEAL, MATTHEW D, NOVELLI, ENRICO M · 2019 to 2022
$3.1MPlatelet-inspired Delivery System for Targeted Thrombolytic TherapyR01HL129179 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI SEN GUPTA, ANIRBAN · 2015 to 2018
$1.8MLeica SP8 Confocal with Hyvolution2 DeconvolutionS10OD024996 · OD · CASE WESTERN RESERVE UNIVERSITY · PI IMANISHI, YOSHIKAZU · 2018 to 2018
$594kNHLBI NIH HHS R01 HL098217NHLBI NIH HHS R01 HL121212NHLBI NIH HHS R01 HL129179NHLBI NIH HHS R01 HL141080NIGMS NIH HHS R35 GM119526NIGMS NIH HHS T32 GM008803NIH HHS S10 OD024996
Abstract
Severe hemorrhage associated with trauma, surgery, and congenital or drug-induced coagulopathies can be life-threatening and requires rapid hemostatic management via topical, intracavitary, or intravenous routes. For injuries that are not easily accessible externally,
Indexed as
HemostaticsThrombinAnimalsAnticoagulantsBlood PlateletsFibrinFibrinogenHemostasisHumansLiposomesMiceNanomedicineNanoparticlesPolymersvon Willebrand FactorAnticoagulantsFibrinFibrinogenHemostaticsLipid NanoparticlesLiposomesPolymersThrombinvon Willebrand FactorFibrinHemostasisNanoparticlePlateletsTargeted deliveryThrombin
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.