Evidence map›Paper›PMID 35916457›Full record

SynthesisJBRA assisted reproduction2023

Polycystic ovaries and herbal remedies: A systematic review.

Aliasghar Manouchehri, Saber Abbaszadeh, Mahdeyeh Ahmadi, Fateme Khajoei Nejad, Mahmoud Bahmani, Neda Dastyar

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in JBRA assisted reproduction, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07603505 (Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07603505 phase1completednot on this mapstarted 2025, after this paper: background citation

Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome (PCOS)

TypeinterventionalSponsorJinnah Sindh Medical UniversityRan2025 to 2026Enrolled116ConditionsPolycystic Ovarian Syndrome (PCOS), Infertility, Metabolic DisordersArmsHerbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  14. Therapeutic Potential ofAntioxidants (Basel, Switzerland) · 2025
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  17. 3 Biotech · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Aliasghar ManouchehriAssistant Professor, Department of Internal Medicine, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran.
Saber AbbaszadehDepartment of Biochemistry And Genetics, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mahdeyeh AhmadiMedical School, Jiroft University of Medical Sciences, Jiroft, Iran.
Fateme Khajoei NejadNursing and Midwifery School, Kerman University of Medical Sciences, Kerman, Iran.
Mahmoud BahmaniBiotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Neda DastyarDepartment of Midwifery, Nursing and Midwifery School, Jiroft University of Medical Sciences, Jiroft, Iran.
University of Jiroft · IRBabol University of Medical Sciences · IRKerman University of Medical Sciences · IRLorestan University of Medical Sciences · IRMedical University of Ilam · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePolycystic ovary syndrome (PCOS) is an endocrine disorder that affects one in every 15 women worldwide. This disorder is mainly characterized by increased levels of male hormones (androgens), acne, and hirsutism, and can lead to long-term insulin resistance, miscarriage, or even infertility in women. PCOS is a disorder that can be treated with natural and allopathic remedies that work against the PCOS mechanism. The present study reviews previous studies on the treatment of PCOS using natural drugs.

methodsThe data in this study were collected from articles published in reputable databases including ScienceDirect, PubMed, Google Scholar, and SID in the field of medicinal plants from 1990 to 2021.

resultsA review of the literature showed that plants such as aloe vera and chamomile improve fertility by increasing the number of ovarian follicles. Besides, Vitex agnus-castus and octane reduce hirsutism by reducing testosterone and androgen levels. It was also shown that liquorice, ginseng, cinnamon, and de chiro Inositol improve the adverse effects of diabetes caused by PCOS by lowering lipid and blood glucose levels. Moreover, Stachys lavandulifolia and fennel are effective in changing endometrial tissue parameters in PCOS by reducing estrogen and hyperplasia.

conclusionsVarious studies have shown that herbal medicines can improve PCOS symptoms in women with minimal side effects but a longer treatment cycle.

Indexed as

Complementary TherapiesInfertilityPolycystic Ovary SyndromeFemaleHirsutismHumanshormonesinfertilitymedicinal plantspolycystic ovary

Identifiers

PMID35916457
PMCPMC10065776
OpenAlexW4289639778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.