Evidence map›Paper›PMID 35916066›Full record

ArticleImmunology and cell biology2022

CD137L and CD4 T cells limit BCL6-expressing pre-germinal center B cell expansion and BCL6-driven B cell malignancy.

Zhoujie Ding, Isaak Quast, Feng Yan, Yang Liao, Catherine Pitt, Kristy O-Donnell, Marcus J Robinson, Wei Shi, Axel Kallies, Dimitra Zotos and 1 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Immunology and cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Zhoujie DingDepartment of Immunology and Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia.ORCID 0000-0001-8765-8814
Isaak QuastDepartment of Immunology and Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia.ORCID 0000-0001-6517-8537
Feng YanAustralian Centre for Blood Diseases, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Yang LiaoOlivia Newton John Cancer Research Institute, Melbourne, VIC, Australia.
Catherine PittDepartment of Immunology and Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia.
Kristy O-DonnellDepartment of Immunology and Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia.
Marcus J RobinsonDepartment of Immunology and Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia.ORCID 0000-0001-5677-3078
Wei ShiOlivia Newton John Cancer Research Institute, Melbourne, VIC, Australia.
Axel KalliesThe Peter Doherty Institute, University of Melbourne, Melbourne, VIC, Australia.
Dimitra ZotosDepartment of Immunology and Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia.
David M TarlintonDepartment of Immunology and Pathology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, VIC, Australia.ORCID 0000-0001-9928-686X
Monash Alfred Psychiatry Research centre · AUAustralian Centre for HIV and Hepatitis Virology Research · AULa Trobe University · AUOlivia Newton-John Cancer Wellness & Research Centre · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant expression of the proto-oncogene BCL6 is a driver of tumorigenesis in diffuse large B cell lymphoma (DLBCL). Mice overexpressing BCL6 from the B cell-specific immunoglobulin heavy chain μ intron promoter (Iμ-Bcl6

Indexed as

4-1BB LigandLymphoma, Large B-Cell, DiffuseAnimalsCD4-Positive T-LymphocytesGerminal CenterHumansImmunoglobulin Heavy ChainsMiceProto-Oncogene Proteins c-bcl-64-1BB LigandBCL6 protein, humanBcl6 protein, mouseImmunoglobulin Heavy ChainsProto-Oncogene Proteins c-bcl-6B cell malignancyBCL6CD137LCD4 T cellstumor immunity

Identifiers

PMID35916066
OpenAlexW4289520168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.