Evidence map›Paper›PMID 35915784›Full record

ArticleThe Lancet regional health. Europe2022

Omicron SARS-CoV-2 epidemic in England during February 2022: A series of cross-sectional community surveys.

Marc Chadeau-Hyam, David Tang, Oliver Eales, Barbara Bodinier, Haowei Wang, Jakob Jonnerby, Matthew Whitaker, Joshua Elliott, David Haw, Caroline E Walters and 11 more

Open access · goldAbstract read
In one paragraph

Article in The Lancet regional health. Europe, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 6 institutions in 2 countries.

Marc Chadeau-HyamSchool of Public Health, Imperial College London, UK.
David TangSchool of Public Health, Imperial College London, UK.
Oliver EalesSchool of Public Health, Imperial College London, UK.
Barbara BodinierSchool of Public Health, Imperial College London, UK.
Haowei WangSchool of Public Health, Imperial College London, UK.
Jakob JonnerbySchool of Public Health, Imperial College London, UK.
Matthew WhitakerSchool of Public Health, Imperial College London, UK.
Joshua ElliottImperial College Healthcare NHS Trust, UK.
David HawSchool of Public Health, Imperial College London, UK.
Caroline E WaltersSchool of Public Health, Imperial College London, UK.
Christina AtchisonSchool of Public Health, Imperial College London, UK.
Peter J DiggleCHICAS, Lancaster Medical School, Lancaster University, UK and Health Data Research, UK.
Andrew J PageQuadram Institute, Norwich, UK.
Deborah AshbySchool of Public Health, Imperial College London, UK.
Wendy BarclayDepartment of Infectious Disease, Imperial College London, UK.
Graham TaylorDepartment of Infectious Disease, Imperial College London, UK.
Graham CookeImperial College Healthcare NHS Trust, UK.
Helen WardSchool of Public Health, Imperial College London, UK.
Ara DarziImperial College Healthcare NHS Trust, UK.
Christl A DonnellySchool of Public Health, Imperial College London, UK.
Paul ElliottSchool of Public Health, Imperial College London, UK.
Imperial College London · GBImperial College Healthcare NHS Trust · GBNational Centre for Infectious Diseases · SGHealth Data Research UK · GBQuadram Institute · GBUniversity of Oxford · GB

Funding

Cancer Research UK 22184Medical Research Council MC_PC_19012Medical Research Council MR/L01341X/1Medical Research Council MR/R015600/1Medical Research Council MR/S019669/1Wellcome Trust
6 · The paper itself

Abstract

Background: The Omicron wave of COVID-19 in England peaked in January 2022 resulting from the rapid transmission of the Omicron BA.1 variant. We investigate the spread and dynamics of the SARS-CoV-2 epidemic in the population of England during February 2022, by region, age and main SARS-CoV-2 sub-lineage. Methods: In the REal-time Assessment of Community Transmission-1 (REACT-1) study we obtained data from a random sample of 94,950 participants with valid throat and nose swab results by RT-PCR during round 18 (8 February to 1 March 2022). Findings: We estimated a weighted mean SARS-CoV-2 prevalence of 2.88% (95% credible interval [CrI] 2.76-3.00), with a within-round effective reproduction number (R) overall of 0.94 (0·91-0.96). While within-round weighted prevalence fell among children (aged 5 to 17 years) and adults aged 18 to 54 years, we observed a level or increasing weighted prevalence among those aged 55 years and older with an R of 1.04 (1.00-1.09). Among 1,616 positive samples with sublineages determined, one (0.1% [0.0-0.3]) corresponded to XE BA.1/BA.2 recombinant and the remainder were Omicron: Interpretation: In February 2022, infection prevalence in England remained high with level or increasing rates of infection in older people and an uptick in hospitalisations. Ongoing surveillance of both survey and hospitalisations data is required. Funding: Department of Health and Social Care, England.

Indexed as

BA.2 sublineageb-spline, basis splineCOVID-19Ct, Cycle thresholdLTLA, Lower-Tier Local AuthorityNHS, National Health ServiceOmicron variantP-spline, penalised splineRandom community surveysrim, random iterative methodRT-PCR, Reverse Transcription Polymerase Chain ReactionSARS-CoV-2UKHSA, UK Health Security Agency

Identifiers

PMID35915784
PMCPMC9330654
OpenAlexW4288420760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.