Evidence map›Paper›PMID 35915497›Full record

ArticleCardiovascular ultrasound2022

A novel echocardiographic right ventricular dysfunction score can identify hemodynamic severity profiles in left ventricular dysfunction.

Odd Bech-Hanssen, Martin Fredholm, Marco Astengo, Sven-Erik Bartfay, Entela Bollano, Göran Dellgren, Kristjan Karason, Sven-Erik Ricksten

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular ultrasound, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Right Ventricular Dysfunction Score in the Prognostic Evaluation of Patients with Sepsis and Septic Shock.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Odd Bech-HanssenDepartment of Clinical Physiology, Institute of Medicine at the Sahlgrenska Academy, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden. odd.bech-hanssen@klinfys.gu.se.
Martin FredholmInstitution of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Marco AstengoDepartment of Clinical Physiology, Institute of Medicine at the Sahlgrenska Academy, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Sven-Erik BartfayInstitution of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Entela BollanoInstitution of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Göran DellgrenInstitution of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Kristjan KarasonInstitution of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Sven-Erik RickstenInstitution of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
University of Gothenburg · SESahlgrenska University Hospital · SE

Funding

Hjärt-Lungfonden 20110377
6 · The paper itself

Abstract

purposeRecognition of congestion and hypoperfusion in patients with chronic left ventricular dysfunction (LVD) has therapeutic and prognostic implications. In the present study we hypothesized that a multiparameter echocardiographic grading of right ventricular dysfunction (RVD) can facilitate the characterization of hemodynamic profiles.

methodsConsecutive patients (n = 105, age 53 ± 14 years, males 77%, LV ejection fraction 28 ± 11%) referred for heart transplant or heart failure work-up, with catheterization and echocardiography within 48 h, were reviewed retrospectively. Three hemodynamic profiles were defined: compensated LVD (cLVD, normal pulmonary capillary wedge pressure (PCWP < 15 mmHg) and normal mixed venous saturation (SvO

resultsThe RVD score [median (IQR 25%;75%)] showed significant in-between the three groups differences with 1 (0;1), 1 (0.5;2) and 3.0 (2;3.5) in patients with cLVD, dLVD and LVF, respectively. The finding of RVD score ≥ 2 or ≥ 4 increased the likelihood of decompensation or LVF 5.2-fold and 6.7-fold, respectively. On the contrary, RVD score < 1 and < 2 reduced the likelihood 11.1-fold and 25-fold, respectively. The RVD score was more helpful than standard echocardiography regarding identification of hemodynamic profiles.

conclusionsIn this proof of concept study an echocardiographic RVD score identified different hemodynamic severity profiles in patients with chronic LVD and reduced ejection fraction. Further studies are needed to validate its general applicability.

Indexed as

Heart FailureVentricular Dysfunction, LeftVentricular Dysfunction, RightAdultAgedEchocardiographyHemodynamicsHumansMaleMiddle AgedRetrospective StudiesStroke VolumeVentricular Function, RightEchocardiographyHemodynamic profileLeft ventricular dysfunctionRight ventricular dysfunction score

Identifiers

PMID35915497
PMCPMC9344733
OpenAlexW4289313414

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.