Evidence map›Paper›PMID 35915457›Full record

SynthesisBMC medical informatics and decision making2022

Machine learning algorithms' accuracy in predicting kidney disease progression: a systematic review and meta-analysis.

Nuo Lei, Xianlong Zhang, Mengting Wei, Beini Lao, Xueyi Xu, Min Zhang, Huifen Chen, Yanmin Xu, Bingqing Xia, Dingjun Zhang and 4 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC medical informatics and decision making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  13. Derivation and Validation of a Machine Learning Model for the Prevention of Unplanned Dialysis.Clinical journal of the American Society of Nephrology : CJASN · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Nuo Lei *The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Xianlong Zhang *Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Mengting WeiThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Beini LaoThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Xueyi XuThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Min ZhangThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Huifen ChenThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Yanmin XuThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Bingqing XiaThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Dingjun ZhangThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Chendi DongThe Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
Lizhe FuChronic Disease Management Department, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Fang TangChronic Disease Management Department, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Yifan WuDepartment of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. wuyifan007@gzucm.edu.cn.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney disease progression rates vary among patients. Rapid and accurate prediction of kidney disease outcomes is crucial for disease management. In recent years, various prediction models using Machine Learning (ML) algorithms have been established in nephrology. However, their accuracy have been inconsistent. Therefore, we conducted a systematic review and meta-analysis to investigate the diagnostic accuracy of ML algorithms for kidney disease progression.

methodsWe searched PubMed, EMBASE, Cochrane Central Register of Controlled Trials, the Chinese Biomedicine Literature Database, Chinese National Knowledge Infrastructure, Wanfang Database, and the VIP Database for diagnostic studies on ML algorithms' accuracy in predicting kidney disease prognosis, from the establishment of these databases until October 2020. Two investigators independently evaluate study quality by QUADAS-2 tool and extracted data from single ML algorithm for data synthesis using the bivariate model and the hierarchical summary receiver operating characteristic (HSROC) model.

resultsFifteen studies were left after screening, only 6 studies were eligible for data synthesis. The sample size of these 6 studies was 12,534, and the kidney disease types could be divided into chronic kidney disease (CKD) and Immunoglobulin A Nephropathy, with 5 articles using end-stage renal diseases occurrence as the primary outcome. The main results indicated that the area under curve (AUC) of the HSROC was 0.87 (0.84-0.90) and ML algorithm exhibited a strong specificity, 95% confidence interval and heterogeneity (I

conclusionTaking advantage of big data, ML algorithm-based prediction models have high accuracy in predicting kidney disease progression, we recommend ML algorithms as an auxiliary tool for clinicians to determine proper treatment and disease management strategies.

Indexed as

Machine LearningRenal Insufficiency, ChronicAlgorithmsDisease ProgressionHumansKidneyArtificial intelligenceChronic kidney diseaseCKD progressionImmunoglobulin A nephropathyMachine learning algorithmPrediction models

Identifiers

PMID35915457
PMCPMC9341041
OpenAlexW4289201638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.