Evidence map›Paper›PMID 35915454›Full record

ArticleHealth and quality of life outcomes2022

Quantitative and qualitative analysis of the quality of life of Type 1 diabetes patients using insulin pumps and of those receiving multiple daily insulin injections.

Lilian Tzivian, Jelizaveta Sokolovska, Anna E Grike, Agate Kalcenaua, Abraham Seidmann, Arriel Benis, Martins Mednis, Ieva Danovska, Ugis Berzins, Arnolds Bogdanovs and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Type 1 diabetes stigma: A UK survey of adults living with type 1 diabetes.Diabetic medicine : a journal of the British Diabetic Association · 2026
    Observational
  3. Review
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Lilian TzivianFaculty of Medicine, University of Latvia, Jelgavas Str. 3, Riga, Latvia. Liliana.Civjane@lu.lv.
Jelizaveta SokolovskaFaculty of Medicine, University of Latvia, Jelgavas Str. 3, Riga, Latvia.
Anna E GrikeFaculty of Humanities, University of Latvia, Riga, Latvia.
Agate KalcenauaFaculty of Medicine, Riga Stardins University, Riga, Latvia.
Abraham SeidmannQuestrom Business School, Boston University, Boston, MA, 02215, USA.
Arriel BenisFaculty of Industrial Engineering and Technology Management, Holon Institute of Technology, 5810201, Holon, Israel.
Martins MednisLongenesis Ltd, Riga, Latvia.
Ieva DanovskaLongenesis Ltd, Riga, Latvia.
Ugis BerzinsLongenesis Ltd, Riga, Latvia.
Arnolds BogdanovsLongenesis Ltd, Riga, Latvia.
Emil SyundyukovLongenesis Ltd, Riga, Latvia.
University of Latvia · LVBoston University · USHolon Institute of Technology · ILRiga Stradiņš University · LV

Funding

Medtronic B.V. Representative Office in Latvia partial support
6 · The paper itself

Abstract

introductionInsulin pump therapy represents an alternative to multiple daily injections and can improve glycemic control and quality of life (QoL) in Type 1 diabetes mellitus (T1DM) patients. We aimed to explore the differences and factors related to the T1DM-specific QoL of such patients in Latvia. DESIGN AND

methodsA mixed-method cross-sectional study on 87 adult T1DM patients included 20 pump users and 67 users of injections who participated in the quantitative part of the study; 8 pump users and 13 injection users participated in the qualitative part. Patients were invited to participate using a dedicated digital platform. Their QoL and self-management habits were assessed using specially developed questionnaires adapted to Latvian conditions. Multiple logistic regression models were built to investigate the association between social and self-management factors and patients' QoL. In addition, qualitative analysis of answers was performed.

resultsInsulin pump users were younger, had higher incomes, and reported higher T1DM expenses than users of multiple daily injections. There were no differences in self-management between the groups; Total QoL differed at the 0.1 significance level. In fully adjusted multiple logistic regression models, the most important factor that increased Total QoL was lower T1DM-related expenses (odds ratio, OR 7.02 [95% confidence interval 1.29; 38.0]). Men and those with more years of living with T1DM had better QoL (OR 9.62 [2.20; 42.1] and OR 1.16 [1.05; 1.29], respectively), but the method of administration was not significantly associated with QoL (OR 7.38 [0.87; 62.9]). Qualitative data supported the results of quantitative analysis.

conclusionsQoL was the main reason to use an insulin pump, while the expense was the main reason to avoid the use of it or to stop using it. Reimbursement policies thus should be considered to enable patients to choose the more convenient method for themselves.

Indexed as

Diabetes Mellitus, Type 1AdultCross-Sectional StudiesFemaleGlycated HemoglobinHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsMaleQuality of LifeGlycated HemoglobinHypoglycemic AgentsInsulinComparative effectiveness researchDiabetes-related expensesHealth economicsInsulin pumpMultiple daily insulin injectionsQuality of lifeReal World Data digital toolType 1 diabetes mellitus

Identifiers

PMID35915454
PMCPMC9344781
OpenAlexW4289317935

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.