ArticleScientific reports2022
The interplay between cognition, depression, anxiety, and sleep in primary Sjogren's syndrome patients.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and influencing factors of kinesiophobia after total knee arthroplasty: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Development and validation of a nomogram for predicting fatigue in patients with primary Sjögren's syndrome.Clinical rheumatology · 2024Trial
- Agomelatine for Sjögren's syndrome: a study on its therapeutic effects and mechanisms.Inflammopharmacology · 2026Article
- When Dryness Extends to the Brain: Brain-Related Non-Sicca Manifestations of Sjögren's Disease.Journal of clinical medicine · 2026Review
- Beyond Dryness: Mapping the Psychological and Cognitive Burden in Sjögren's Disease-A Narrative Review.Journal of clinical medicine · 2026Review
- Using objective measures of physical activity, sleep, and breathing for disease profiling of patients with systemic lupus erythematosus and Sjögren's disease.Frontiers in digital health · 2026Article
- Association of inflammatory markers with depression and anxiety in female patients with primary Sjögren's syndrome.Biochemia medica · 2025Article
- Can real-world measures of activity, sleep, and cardiorespiratory function stratify Sjogren's disease participants with persistent fatigue? Insights from the BRC tools study.EULAR rheumatology open · 2025Article
- Frequency-dependent and temporal variability of low-frequency fluctuations in patients with primary Sjögren's syndrome.Lupus science & medicine · 2025Article
- Regional brain function study in patients with primary Sjögren's syndrome.Arthritis research & therapy · 2025Article
- Sjögren's syndrome increased risk of attempted suicide.Scientific reports · 2025Article
- Cognitive profile in burning mouth syndrome versus mild cognitive impairment: A comparative study.Oral diseases · 2025Article
- Age-associated B cell infiltration in salivary glands represents a hallmark of Sjögren's-like disease in aging mice.GeroScience · 2024Article
- Sleep Disorders in Connective Tissue Diseases-Coexisting Diseases or Disease Components?Journal of clinical medicine · 2024Review
- Fatigue and sleep quality in Chinese adults with connective tissue disease: A cross-sectional study.Sleep & breathing = Schlaf & Atmung · 2024Article
- The Physical and Psychosocial Impact of Fatigue among Patients with Sjogren's Syndrome: A Systematic Review.Journal of clinical medicine · 2024Review
- Sjögren's syndrome and Parkinson's Disease: A bidirectional two-sample Mendelian randomization study.PloS one · 2024Observational
- Time Use and Cognitive Achievement among Adolescents in China: Depression Symptoms as Mediators.Journal of Intelligence · 2023Article
- Central Nervous System Involvement in Primary Sjögren's Syndrome: Narrative Review of MRI Findings.Diagnostics (Basel, Switzerland) · 2022Review
- Article
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Primary Sjögren's syndrome (pSS) is an autoimmune disease with frequent neurological involvement. Memory complaints are common, but their precise patterns remain unclear. We wanted to characterize patterns of neurocognitive profiles in pSS patients with cognitive complaints. Only pSS patients with memory complaints were included, prospectively. Cognitive profiles were compiled through a comprehensive cognitive evaluation by neuropsychologists. Evaluations of anxiety, depression, fatigue, sleep disorders and quality of life were performed for testing their interactions with cognitive profiles. All 32 pSS patients showed at least borderline cognitive impairment, and 17 (53%) exhibited a pathological cognitive profile: a hippocampal profile (37%), a dysexecutive profile (22%), and an instrumental profile (16%) (possible overlap). Regarding the secondary objectives: 37% of patients were depressed, and 48% exhibited a mild-to-severe anxiety trait. Sleep disorders were frequent (excessive daytime sleepiness (55%), high risk for sleep apnea (45%), and insomnia (77%)). Cognitive impairments could not be explained alone by anxiety, depression or sleep disorders. Fatigue level was strongly associated with sleep disorders. Our study highlights that cognitive complaints in pSS patients are supported by measurable cognitive impairments, apart from frequently associated disorders such as depression, anxiety or sleep troubles. Sleep disorders should be screened.
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