ArticleNature ecology & evolution2022
The role of mitochondrial energetics in the origin and diversification of eukaryotes.
Article in Nature ecology & evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed.
- Host-initiated microbial association leads to stable ectosymbiosis in an ecological model.PLoS computational biology · 2026Article
- Deep-learning deconvolution and segmentation of fluorescent membranes for high-precision bacterial cell-size profiling.Communications biology · 2026Article
- Heart-homed nanomedicine induces fast mitochondrial rescue to enhance cardiac function post-myocardial infarction.Bioactive materials · 2026Article
- Demand-only energetics at 120 ATP per glucose: A reply to Lynch.Biochimica et biophysica acta. Bioenergetics · 2026Article
- Energetics and evolution: Response to Martin.Biochimica et biophysica acta. Bioenergetics · 2026Article
- The archaeal roots of eukaryotic life.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Eukaryogenesis: Did an Oxidative Crucible Result in Misleading Bioinformatic Analyses?BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- Update on the correlation between mitochondrial function and osteonecrosis of the femoral head osteocytes.Redox report : communications in free radical research · 2025Review
- Quantifying the fitness contribution of phagocytosis.bioRxiv : the preprint server for biology · 2025Article
- Eukaryogenesis From FECA to LECA: Radical Steps Along the Way.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Resource allocation to cell envelopes and the scaling of bacterial growth rate.Physical biology · 2025Article
- Mitochondrial transplantation: adaptive bio-enhancement.Cell death & disease · 2025Article
- The Anatomical and Evolutionary Impact of Pain, Pleasure, Motivation, and Cognition: Integrating Energy Metabolism and the Mind-Body BERN (Behavior, Exercise, Relaxation, and Nutrition) Framework.International journal of molecular sciences · 2025Review
- Bioenergetics and the Evolution of Cellular Traits.Annual review of biophysics · 2025Review
- Quantifying the evolutionary paths to endomembranes.Cell reports · 2025Article
- β-Catenin Regulates Glycolytic and Mitochondrial Function in T-Cell Acute Lymphoblastic Leukemia.Biomedicines · 2025Article
- Demystifying anaerobic respiration: a problem-solving exercise.Journal of microbiology & biology education · 2024Article
- Review
- Apolipoprotein A-I: Potential Protection Against Intestinal Injury Induced by Dietary Lipid.Journal of inflammation research · 2024Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The origin of eukaryotic cell size and complexity is often thought to have required an energy excess supplied by mitochondria. Recent observations show energy demands to scale continuously with cell volume, suggesting that eukaryotes do not have higher energetic capacity. However, respiratory membrane area scales superlinearly with the cell surface area. Furthermore, the consequences of the contrasting genomic architectures between prokaryotes and eukaryotes have not been precisely quantified. Here, we investigated (1) the factors that affect the volumes at which prokaryotes become surface area-constrained, (2) the amount of energy divested to DNA due to contrasting genomic architectures and (3) the costs and benefits of respiring symbionts. Our analyses suggest that prokaryotes are not surface area-constrained at volumes of 10
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