Evidence map›Paper›PMID 35914340›Full record

ArticleComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society2022

Virtual contrast enhancement for CT scans of abdomen and pelvis.

Jingya Liu, Yingli Tian, Cihan Duzgol, Oguz Akin, A Muhteşem Ağıldere, K Murat Haberal, Mehmet Coşkun

Open access · greenAbstract read
In one paragraph

Article in Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jingya LiuThe City College of New York, New York, NY 10031, USA.
Yingli TianThe City College of New York, New York, NY 10031, USA. Electronic address: ytian@ccny.cuny.edu.
Cihan DuzgolMemorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Oguz AkinMemorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: akino@mskcc.org.
A Muhteşem AğıldereBaşkent University, Ankara 06810, Turkey.
K Murat HaberalBaşkent University, Ankara 06810, Turkey.
Mehmet CoşkunBaşkent University, Ankara 06810, Turkey.
Başkent University · TRCity College of New York · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Contrast agents are commonly used to highlight blood vessels, organs, and other structures in magnetic resonance imaging (MRI) and computed tomography (CT) scans. However, these agents may cause allergic reactions or nephrotoxicity, limiting their use in patients with kidney dysfunctions. In this paper, we propose a generative adversarial network (GAN) based framework to automatically synthesize contrast-enhanced CTs directly from the non-contrast CTs in the abdomen and pelvis region. The respiratory and peristaltic motion can affect the pixel-level mapping of contrast-enhanced learning, which makes this task more challenging than other body parts. A perceptual loss is introduced to compare high-level semantic differences of the enhancement areas between the virtual contrast-enhanced and actual contrast-enhanced CT images. Furthermore, to accurately synthesize the intensity details as well as remain texture structures of CT images, a dual-path training schema is proposed to learn the texture and structure features simultaneously. Experiment results on three contrast phases (i.e. arterial, portal, and delayed phase) show the potential to synthesize virtual contrast-enhanced CTs directly from non-contrast CTs of the abdomen and pelvis for clinical evaluation.

Indexed as

AbdomenTomography, X-Ray ComputedHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPelvisContrast enhanced CTDeep learningGenerative adversarial networkImage synthesize

Identifiers

PMID35914340
PMCPMC10227907
OpenAlexW4288045091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.