Evidence map›Paper›PMID 35914224›Full record

ArticleBlood advances2023

A monocentric analysis of the long-term safety and efficacy of crizotinib in relapsed/refractory ALK+ lymphomas.

Giovanni Rindone, Andrea Aroldi, Elisa Bossi, Luisa Verga, Giovanni Zambrotta, Sara Tarantino, Rocco Piazza, Lara Mussolin, Roberto Chiarle, Carlo Gambacorti-Passerini

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02419287 (Pilot Study of Crizotinib in Relapsed ALK+ Lymphomas), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02419287 phase2completednot on this map

Pilot Study of Crizotinib in Relapsed ALK+ Lymphomas

TypeinterventionalSponsorUniversity of Milano BicoccaRan2015 to 2022Enrolled12ConditionsAnaplastic Large Cell Lymphoma, ALK-PositiveArmscrizotinib
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Giovanni RindoneHematology Division, San Gerardo Hospital, Monza, Italy.ORCID 0000-0001-9244-4407
Andrea AroldiHematology Division, San Gerardo Hospital, Monza, Italy.
Elisa BossiHematology Division, San Gerardo Hospital, Monza, Italy.
Luisa VergaHematology Division, San Gerardo Hospital, Monza, Italy.
Giovanni ZambrottaHematology Division, San Gerardo Hospital, Monza, Italy.ORCID 0000-0002-8612-2994
Sara TarantinoHematology Division, San Gerardo Hospital, Monza, Italy.
Rocco PiazzaHematology Division, San Gerardo Hospital, Monza, Italy.ORCID 0000-0003-4198-9620
Lara MussolinDepartment of Woman's and Child's Health, University of Padova, Padova, Italy.
Roberto ChiarleDepartment of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.ORCID 0000-0003-1564-8531
Carlo Gambacorti-PasseriniHematology Division, San Gerardo Hospital, Monza, Italy.ORCID 0000-0001-6058-515X
Azienda Ospedaliera San Gerardo · ITBoston Children's Hospital · USUniversity of Padua · IT

Funding

Mechanisms of resistance to ALK inhibitors in ALK-rearranged lymphomaR01CA196703 · NCI · BOSTON CHILDREN'S HOSPITAL · PI CHIARLE, ROBERTO · 2015 to 2025
$4.1M
NCI NIH HHS R01 CA196703
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LymphomaReceptor Protein-Tyrosine KinasesAnaplastic Lymphoma KinaseCrizotinibHumansAnaplastic Lymphoma KinaseCrizotinibReceptor Protein-Tyrosine Kinases

Identifiers

PMID35914224
PMCPMC9898594
OpenAlexW4289277648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.