Evidence map›Paper›PMID 35914221›Full record

ArticleAnnals of the American Thoracic Society2022

Acute Exacerbations Are Associated with Progression of Emphysema.

Surya P Bhatt, Sandeep Bodduluri, Mark T Dransfield, Joseph M Reinhardt, James D Crapo, Edwin K Silverman, Stephen Humphries, David A Lynch, Matthew J Strand

Abstract readLetter
In one paragraph

Article in Annals of the American Thoracic Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Mechanically Affected Lung and Progression of Emphysema.American journal of respiratory and critical care medicine · 2025
    Article
  4. Respiratory Exacerbations Increase with Chronic PMmedRxiv : the preprint server for health sciences · 2025
    Article
  5. Article
  6. Association of Ground-Glass Opacities with Systemic Inflammation and Progression of Emphysema.American journal of respiratory and critical care medicine · 2024
    Article
  7. Article
  8. Article
  9. Phenotypes, Etiotypes, and Endotypes of Exacerbations of Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2023
    Review
  10. FEVAmerican journal of respiratory and critical care medicine · 2023
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Surya P BhattUniversity of Alabama at Birmingham Birmingham, Alabama.ORCID 0000-0002-8418-4497
Sandeep BodduluriUniversity of Alabama at Birmingham Birmingham, Alabama.
Mark T DransfieldUniversity of Alabama at Birmingham Birmingham, Alabama.
Joseph M ReinhardtUniversity of Iowa Iowa City, Iowa.
James D CrapoNational Jewish Health Denver, Colorado.
Edwin K SilvermanHarvard Medical School Boston, Massachusetts.
Stephen HumphriesNational Jewish Health Denver, Colorado.ORCID 0000-0002-5113-4530
David A LynchNational Jewish Health Denver, Colorado.
Matthew J StrandNational Jewish Health Denver, Colorado.

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Metabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9M
1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD)UH3HL155806 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Surya P Bhatt · 2022 to 2026
$5.4M
Structural Determinants of Disease Progression in COPDR01HL151421 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BHATT, SURYA P., NAKHMANI, ARIE · 2020 to 2024
$2.6M
1/2 Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease (Tele-COPD)UG3HL155806 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BHATT, SURYA P. · 2021 to 2021
$1.5M
Deep Learning and Fluid Dynamics Based Phenotyping of Expiratory Central Airway CollapseR21EB027891 · NIBIB · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BHATT, SURYA P., RAGHAV, VRISHANK · 2019 to 2021
$599k
UAB Mentoring Program in COPD Patient Oriented ResearchK24HL140108 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DRANSFIELD, MARK T · 2018 to 2022
$439k
NHLBI NIH HHS K24 HL140108NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS R01 HL151421NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NHLBI NIH HHS UG3 HL155806NHLBI NIH HHS UH3 HL155806NIBIB NIH HHS R21 EB027891
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EmphysemaPulmonary Disease, Chronic ObstructivePulmonary EmphysemaDisease ProgressionHumans

Identifiers

PMID35914221
PMCPMC9743469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.