ArticleProceedings of the National Academy of Sciences of the United States of America2022
Chemical inhibition of the auxin inactivation pathway uncovers the roles of metabolic turnover in auxin homeostasis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Comprehensive characterisation of IAA inactivation pathways reveals the impact of glycosylation on auxin metabolism and plant development in Arabidopsis.Communications biology · 2026Article
- Phytohormone and transcriptome analyses unravel the molecular mechanisms of heterophylly in Pinellia ternata.BMC plant biology · 2026Article
- Phenylacetic acid metabolism in land plants: novel pathways and metabolites.Journal of experimental botany · 2025Article
- Exogenous application of the apocarotenoid retinaldehyde negatively regulates auxin-mediated root growth.Plant physiology · 2024Article
- Small chemical molecules regulating the phytohormone signalling alter the plant's physiological processes to improve stress adaptation, growth and productivity.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Genome-wide gene network uncover temporal and spatial changes of genes in auxin homeostasis during fruit development in strawberry (F. × ananassa).BMC plant biology · 2024Article
- Nitrate Starvation Induces Lateral Root Organogenesis inInternational journal of molecular sciences · 2024Article
- Transcriptomic and Physiological Analyses for the Role of Hormones and Sugar in Axillary Bud Development of Wild Strawberry Stolon.Plants (Basel, Switzerland) · 2024Article
- Photosynthetic Activities, Phytohormones, and Secondary Metabolites Induction in Plants by Prevailing Compost Residue.Metabolites · 2024Article
- The Roles of GRETCHEN HAGEN3 (GH3)-Dependent Auxin Conjugation in the Regulation of Plant Development and Stress Adaptation.Plants (Basel, Switzerland) · 2023Review
- Causes and consequences of endogenous hypoxia on growth and metabolism of developing maize kernels.Plant physiology · 2023Article
- Evolutionary Analysis of the Melon (Plants (Basel, Switzerland) · 2023Article
- Auxin regulation on crop: from mechanisms to opportunities in soybean breeding.Molecular breeding : new strategies in plant improvement · 2023Article
- High-Throughput Sequencing Reveals Novel microRNAs Involved in the Continuous Flowering Trait of Longan (International journal of molecular sciences · 2022Article
- Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- New Wine in an Old Bottle: Utilizing Chemical Genetics to Dissect Apical Hook Development.Life (Basel, Switzerland) · 2022Review
- The main oxidative inactivation pathway of the plant hormone auxin.Nature communications · 2021Article
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Authors and funding
11 authors.
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Abstract
The phytohormone auxin, indole-3-acetic acid (IAA), plays a prominent role in plant development. Auxin homeostasis is coordinately regulated by auxin synthesis, transport, and inactivation; however, the physiological contribution of auxin inactivation to auxin homeostasis has not been determined. The GH3 IAA-amino acid conjugating enzymes play a central role in auxin inactivation. Chemical inhibition of GH3 proteins
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