Evidence map›Paper›PMID 35914164›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Long wavelength-emissive Ru(II) metallacycle-based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment.

Yuling Xu, Chonglu Li, Xin Ma, Wei Tuo, Le Tu, Xiaopeng Li, Yan Sun, Peter J Stang, Yao Sun

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 140 citations in OpenAlex.

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  12. Supramolecular coordination platinum metallacycle-based multilevel wound dressing for bacteria sensing and wound healing.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Yuling XuKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, China.
Chonglu LiKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, China.
Xin MaKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, China.
Wei TuoDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112.
Le TuMinistry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecular, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China.
Xiaopeng LiCollege of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China.ORCID 0000-0001-9655-9551
Yan SunDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112.
Peter J StangDepartment of Chemistry, University of Utah, Salt Lake City, UT 84112.ORCID 0000-0002-2307-0576
Yao SunKey Laboratory of Pesticides and Chemical Biology, Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, China.
Central China Normal University · CNHenan University · CNUniversity of Utah · USHubei University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ruthenium (Ru) complexes are developed as latent emissive photosensitizers for cancer and pathogen photodiagnosis and therapy. Nevertheless, most existing Ru complexes are limited as photosensitizers in terms of short excitation and emission wavelengths. Herein, we present an emissive Ru(II) metallacycle (herein referred to as 1) that is excited by 808-nm laser and emits at a wavelength of ∼1,000 nm via coordination-driven self-assembly. Metallacycle 1 exhibits good optical penetration (∼7 mm) and satisfactory reactive oxygen species production properties. Furthermore, 1 shows broad-spectrum antibacterial activity (including against drug-resistant

Indexed as

Bacterial InfectionsCoordination ComplexesPhotochemotherapyPhotosensitizing AgentsRutheniumAnimalsAnti-Bacterial AgentsBacteriaEscherichia coliLightMiceStaphylococcus aureusAnti-Bacterial AgentsCoordination ComplexesPhotosensitizing AgentsRutheniumlong-wavelength emissivemetallacyclesupramolecular coordination complexes

Identifiers

PMID35914164
PMCPMC9371697
OpenAlexW4289261656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.