Evidence map›Paper›PMID 35913205›Full record

ArticleMicrobiology spectrum2022

Increased Prevalence of Lassa Fever Virus-Positive Rodents and Diversity of Infected Species Found during Human Lassa Fever Epidemics in Nigeria.

Anise N Happi, Testimony J Olumade, Olusola A Ogunsanya, Ayotunde E Sijuwola, Seto C Ogunleye, Judith U Oguzie, Cecilia Nwofoke, Chinedu A Ugwu, Samuel J Okoro, Patricia I Otuh and 8 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
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  11. Article
  12. Article
  13. Strategies of rational and structure-driven vaccine design for Arenaviruses.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2024
    Review
  14. Lassa Fever: Critical Review and Prospects for Control.Tropical medicine and infectious disease · 2024
    Review
  15. Modelling Lassa virus dynamics in West AfricanJournal of the Royal Society, Interface · 2024
    Article
  16. Article
  17. Review
  18. Lassa Virus Structural Biology and Replication.Current topics in microbiology and immunology · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 2 countries.

Anise N HappiAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.ORCID 0000-0001-8959-5175
Testimony J OlumadeAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.ORCID 0000-0002-5046-153X
Olusola A OgunsanyaAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.
Ayotunde E SijuwolaAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.
Seto C OgunleyeUniversity of Ibadan, Ibadan, Oyo, Nigeria.
Judith U OguzieAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.
Cecilia NwofokeAlex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.
Chinedu A UgwuAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.
Samuel J OkoroAlex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.
Patricia I OtuhMichael Okpara University of Agriculture, Umudike, Abia, Nigeria.
Louis N NgeleAlex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria.
Oluwafemi O OjoFederal Medical Centre, Owo, Ondo, Nigeria.
Ademola AdelabuRufus Giwa Polytechnic, Owo, Ondo, Nigeria.
Roseline F AdeleyeFederal Medical Centre, Owo, Ondo, Nigeria.
Nicholas E OyejideAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.
Clinton S NjakaZeal Veterinary Services, Enugu, Enugu, Nigeria.
Jonathan L HeeneyLab of Viral Zoonotics, University of Cambridgegrid.5335.0, Cambridge, United Kingdom.
Christian T HappiAfrican Centre of Excellence for Genomics of Infectious Disease, Redeemer's University, Ede, Osun, Nigeria.
Redeemer's University · NGFederal Teaching Hospital Abakaliki · NGFederal Medical Centre · NGEnugu State University of Science and Technology · NGMichael Okpara University of Agriculture · NGRufus Giwa PolytechnicUniversity of Cambridge · GBUniversity of Ibadan · NG

Funding

Biotechnology and Biological Sciences Research Council BB/R020116/1
6 · The paper itself

Abstract

The dynamics of Lassa virus (LASV) infections in rodent reservoirs and their endemic human caseloads remain poorly understood. During the endemic period, human infections are believed to be associated with the seasonal migration of Mastomys natalensis, thought to be the primary reservoir that triggers multiple spillovers of LASV to humans. It has become imperative to improve LASV diagnosis in rodents while updating their prevalence in two regions of Lassa fever endemicity in Nigeria. Rodents (total, 942) were trapped in Ondo (531) and Ebonyi (411) states between October 2018 and April 2020 for detection of LASV using various tissues. Overall, the LASV prevalence was 53.6%. The outbreak area sampled in Ondo had three and two times higher capture success and LASV prevalence, respectively, than Ebonyi State. This correlated with the higher number of annual cases of Lassa fever (LF) in Ondo State versus Ebonyi State. All rodent genera (

Indexed as

EpidemicsLassa FeverAnimalsHumansLassa virusMurinaeNigeriaPrevalenceRatsinfected tissuesLassa diagnosisLassa feverLassa virusNigeriasmall rodents

Identifiers

PMID35913205
PMCPMC9430508
OpenAlexW4289338337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.