ArticleMicrobiology spectrum2022
Landscapes of Enteric Virome Signatures in Early-Weaned Piglets.
Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Differences in Intestinal Flora and Its Related Metabolite Between Healthy and Diarrheal Piglets: Strategies for Innovative Bacterial Diarrhea Prevention.Animals : an open access journal from MDPI · 2026Article
- Metagenomic sequencing reveals the dynamic changes of pig gut fungal composition following the ages and identifies fungal species associated with diarrhea in piglets.Animal microbiome · 2026Article
- Multi-kingdom fecal microbiome and virus-host interactions associated with growth performance of indigenous beef calves in Guizhou.BMC microbiology · 2026Article
- An approach for diagnosis of diarrhea in neonatal piglets based on the core gut microbiota and machine learning.Frontiers in microbiology · 2026Article
- On-top arginine supplementation during lactation affects milk composition, performance, and intestinal bacterial and viral microbial community of sows and their piglets.Journal of animal science · 2025Article
- Chinese Herbal Medicines as Natural Alternative Products to Antibiotics in Weaned Piglets through Intestinal Microbiota Regulation.International journal of molecular sciences · 2024Article
- Massive expansion of the pig gut virome based on global metagenomic mining.NPJ biofilms and microbiomes · 2024Article
- Developmental Dynamics of the Gut Virome in Tibetan Pigs at High Altitude: A Metagenomic Perspective across Age Groups.Viruses · 2024Article
- Prospects and Challenges of Bacteriophage Substitution for Antibiotics in Livestock and Poultry Production.Biology · 2024Review
- Characteristics of the Fecal Microbiome of Piglets with Diarrhea Identified Using Shotgun Metagenomics Sequencing.Animals : an open access journal from MDPI · 2023Article
- Combining 16S rRNA Sequencing and Metabolomics Data to Decipher the Interactions between Gut Microbiota, Host Immunity, and Metabolites in Diarrheic Young Small Ruminants.International journal of molecular sciences · 2023Article
- Longitudinal Investigation of Enteric Virome Signatures from Parental-Generation to Offspring Pigs.Microbiology spectrum · 2023Article
- Metagenomic Sequencing Identified Specific Bacteriophage Signature Discriminating between Healthy and Diarrheal Neonatal Piglets.Nutrients · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diarrhea caused by early-weaning-induced stress can increase mortality rates and reduce growth performance of piglets, seriously harming the livestock industry. To date, studies on the gut microbiome of early-weaned piglets have focused almost exclusively on bacteria, while studies on their gut virome are extremely lacking. Here, we used metagenomic and metatranscriptomic sequencing combined with bioinformatic analysis techniques to preliminarily characterize the intestinal virome of early-weaned piglets at different biological classification levels. The alpha diversity of enteroviruses was generally elevated in early-weaned piglets with diarrhea, compared to healthy piglets, whereas the two groups of piglets showed no significant difference in beta diversity. In addition, the species compositions of the gut virome were similar between healthy piglets and piglets with diarrhea, while their respective dominant species were somewhat different. We also identified 58 differential DNA viruses and 16 differential RNA viruses between the two groups of piglets at all biological taxonomic levels. Of these, 1 (family
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.