Evidence map›Paper›PMID 35913157›Full record

ArticlemBio2022

Phosphoglucose Isomerase Is Important for

Yao Zhou, Kaizhou Yan, Qijian Qin, Olawale G Raimi, Chao Du, Bin Wang, Chukwuemeka Samson Ahamefule, Bartosz Kowalski, Cheng Jin, Daan M F van Aalten and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Compromising UDP-sugar nucleotide biosynthesis attenuatesCell surface (Amsterdam, Netherlands) · 2026
    Article
  5. Glycolysis enzymes and cellular lactylation in tumour.Clinical and translational medicine · 2026
    Review
  6. Article
  7. Journal of fungi (Basel, Switzerland) · 2025
    Article
  8. Food chemistry. Molecular sciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. D-Limonene InhibitsMolecules (Basel, Switzerland) · 2024
    Article
  13. Article
  14. International journal of molecular sciences · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yao Zhou *Guangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciencesgrid.418329.5, Nanning, Guangxi, China.
Kaizhou Yan *School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.
Qijian QinGuangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciencesgrid.418329.5, Nanning, Guangxi, China.
Olawale G RaimiSchool of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.
Chao DuGuangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciencesgrid.418329.5, Nanning, Guangxi, China.
Bin WangGuangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciencesgrid.418329.5, Nanning, Guangxi, China.
Chukwuemeka Samson AhamefuleGuangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciencesgrid.418329.5, Nanning, Guangxi, China.
Bartosz KowalskiSchool of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.
Cheng JinGuangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciencesgrid.418329.5, Nanning, Guangxi, China.ORCID 0000-0002-1514-6374
Daan M F van AaltenSchool of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.
Wenxia FangGuangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciencesgrid.418329.5, Nanning, Guangxi, China.ORCID 0000-0001-8055-2072
University of Dundee · GBGuangxi Academy of Sciences · CNGuangxi University · CNChinese Academy of Sciences · CN

Funding

Medical Research Council MR/V001094/1Medical Research Council V001094Wellcome Trust 200208/Z/15/Z
6 · The paper itself

Abstract

Aspergillus fumigatus is a devastating opportunistic fungal pathogen causing hundreds of thousands of deaths every year. Phosphoglucose isomerase (PGI) is a glycolytic enzyme that converts glucose-6-phosphate to fructose-6-phosphate, a key precursor of fungal cell wall biosynthesis. Here, we demonstrate that the growth of A. fumigatus is repressed by the deletion of

Indexed as

Aspergillus fumigatusGlucose-6-Phosphate IsomeraseAntifungal AgentsCell WallFungal ProteinsHumansVirulenceAntifungal AgentsFungal ProteinsGlucose-6-Phosphate IsomeraseAspergillus fumigatuscarbon fluxcell walldrug targetfungiphosphoglucose isomerasestructural biology

Identifiers

PMID35913157
PMCPMC9426556
OpenAlexW4289337677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.