ArticleAutism research : official journal of the International Society for Autism Research2022
Examination of pubertal timing and tempo in females and males with autism spectrum disorder compared to typically developing youth.
Article in Autism research : official journal of the International Society for Autism Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Exercise dose architecture as a precision-informed developmental framework in autism spectrum disorder: a narrative review of mechanisms, sex- and development-related heterogeneity, and clinical translation.Frontiers in psychiatry · 2026Pooled it
- Off-Time Puberty in Autism Spectrum Disorder and ADHD: A Scoping Review of Pubertal Timing, Social Cognition, and Psychopathological Risk.Research on child and adolescent psychopathology · 2026Article
- Investigating a biopsychosocial model of depression in autistic youth: The intersection of cortisol and depressive symptoms.Psychoneuroendocrinology · 2026Article
- Adverse Childhood Experiences in Autistic and Neurotypical Girls.Autism research : official journal of the International Society for Autism Research · 2026Article
- Exploring Trajectories of Anxiety Symptoms in Autistic and Non-Autistic Youth over Adolescence Using Parent- and Self-Report Measures.Research in autism · 2026Article
- The contributions of biological maturity and experience to fine motor development in adolescence.Scientific reports · 2026Article
- Examining androgen and estrogen profiles during pubertal development in autistic and neurotypical girls.Hormones and behavior · 2025Article
- The intersection and developmental trajectory of morning cortisol and testosterone in autistic and neurotypical youth.Molecular autism · 2025Article
- Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study.Journal of neurodevelopmental disorders · 2025Article
- Disorders of puberty and neurodevelopment: A shared etiology?Annals of the New York Academy of Sciences · 2024Review
- The relationship between distress tolerance and behavioral activation on anxiety and depression symptomatology in autistic youth: Leveraging self and caregiver perspectives.Autism research : official journal of the International Society for Autism Research · 2024Article
- Gender diversity in autistic and neurotypical youth over adolescence and puberty: A longitudinal study.Autism research : official journal of the International Society for Autism Research · 2024Article
- Trajectory of depressive symptoms over adolescence in autistic and neurotypical youth.Molecular autism · 2024Article
- Pubertal timing in adolescents with ADHD: extension and replication in an all-female sample.European child & adolescent psychiatry · 2024Article
- Salivary testosterone in male and female youth with and without autism spectrum disorder: considerations of development, sex, and diagnosis.Molecular autism · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Autism spectrum disorder (ASD) is characterized by impaired social communication and poor adaptation to change; thus, pubertal development may be precarious. Pubertal timing and tempo were measured in 244 youth (7.9% Black, 83.3% White, and 8.7% multiracial) with ASD (N = 140) and typical development (N = 104). Pubertal development was measured using Tanner staging of Genital (G, males), Breast (B, females), and pubic hair (PH) in both sexes at Year 1 (10-13 years), Year 2 (11-14 years), and Year 3 (12-15 years). Nonlinear mixed effects models analyzed interindividual differences in timing and tempo. For both sexes, ASD and higher body mass index were associated with earlier pubertal timing. Males generally exhibited faster tempo than females. Linear regression models did not show associations between pubertal timing and internalizing symptoms at time three. Findings showing advanced pubertal maturation in ASD youth suggest greater risk of psychological, social, and physiological challenges. LAY SUMMARY: Youth with ASD have difficulty in social communication and adaption to change, thus puberty may be a challenging transition. The study examined onset (timing) and progression (tempo) of puberty over three years, using physical exam, in 244 adolescents with and without ASD, enrolled at ages 10-13. ASD youth started puberty earlier, while males generally progressed at a faster pace. Further examination of puberty in ASD should identify impact on social, behavioral, and mental health outcomes.
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