Evidence map›Paper›PMID 35912826›Full record

ArticleSoft matter2022

Self-assembly of globular proteins with intrinsically disordered protein polyelectrolytes and block copolymers.

Justin M Horn, Yuncan Zhu, So Yeon Ahn, Allie C Obermeyer

Open access · greenAbstract read
In one paragraph

Article in Soft matter, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Engineering Protein-Polyelectrolyte Interactions for Cellular Applications.Annual review of chemical and biomolecular engineering · 2025
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Justin M HornDepartment of Chemical Engineering, Columbia University, New York, NY 10027, USA. aco2134@columbia.edu.ORCID http://orcid.org/0000-0002-7131-6323
Yuncan ZhuDepartment of Chemical Engineering, Columbia University, New York, NY 10027, USA. aco2134@columbia.edu.ORCID http://orcid.org/0000-0002-7038-4877
So Yeon AhnDepartment of Chemical Engineering, Columbia University, New York, NY 10027, USA. aco2134@columbia.edu.ORCID http://orcid.org/0000-0001-9140-2432
Allie C ObermeyerDepartment of Chemical Engineering, Columbia University, New York, NY 10027, USA. aco2134@columbia.edu.ORCID http://orcid.org/0000-0003-2412-2021
Columbia University · US

Funding

Development of functional synthetic biomolecular condensates.R35GM138378 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI OBERMEYER, ALLIE C · 2020 to 2024
$2.3M
NIGMS NIH HHS R35 GM138378
6 · The paper itself

Abstract

Intrinsically disordered polypeptides are a versatile class of materials, combining the biocompatibility of peptides with the disordered structure and diverse phase behaviors of synthetic polymers. Synthetic polyelectrolytes are capable of complex phase behavior when mixed with oppositely charged polyelectrolytes, facilitating nanoparticle formation and bulk phase separation. However, there has been limited exploration of intrinsically disordered protein polyelectrolytes as potential bio-based replacements for synthetic polyelectrolytes. Here, we produce negatively charged, intrinsically disordered polypeptides, capable of high-yield expression in

Indexed as

Intrinsically Disordered ProteinsEscherichia coliPeptidesPolyelectrolytesPolymersIntrinsically Disordered ProteinsPeptidesPolyelectrolytesPolymers

Identifiers

PMID35912826
PMCPMC9446422
OpenAlexW4285171740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.