Evidence map›Paper›PMID 35912741›Full record

ArticleJournal of Alzheimer's disease : JAD2022

Undiagnosed Dementia Is Associated with Poor Physical Function in Older Adults.

Ryan McGrath, Sheria G Robinson-Lane, Lukus Klawitter, Yeong Rhee, Jeremy M Hamm, Mark E McCourt, Kelly Parker, Kyle J Hackney

Open access · greenAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Disparities in glaucoma and macular degeneration healthcare utilization among persons living with dementia in the United States.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ryan McGrathDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
Sheria G Robinson-LaneSchool of Nursing, University of Michigan, Ann Arbor, MI, USA.
Lukus KlawitterDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
Yeong RheeDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
Jeremy M HammDepartment of Psychology, North Dakota State University, Fargo, ND, USA.
Mark E McCourtDepartment of Psychology, North Dakota State University, Fargo, ND, USA.
Kelly ParkerDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
Kyle J HackneyDepartment of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA.
North Dakota State University · USUniversity of Michigan–Ann Arbor · US

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Culturally Responsive Support Programming for Black Caregivers of Persons with DementiaK01AG065420 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROBINSON-LANE, SHERIA GRICE · 2020 to 2024
$639k
NIA NIH HHS K01 AG065420NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

backgroundOlder adults with a cognitive impairment, including those not yet diagnosed, may have deficits in their physical function.

objectiveWe sought to determine the associations of cognitive impairment consistent with dementia (CICD) diagnosis status on handgrip strength, gait speed, and functional disability in older adults.

methodsThe analytical sample included 8,383 adults aged ≥65-years without history of stroke, cancers, neurological conditions, or brain damage who participated in at least one-wave of the 2010-2016 waves of the Health and Retirement Study. A handgrip dynamometer measured handgrip strength. Men with handgrip strength <26 kg and women <16 kg were weak. Gait speed was timed across a 2.5-m course and those with slowness had gait speed <0.8 m/s. Participants with difficulty or an inability in completing any basic activities of daily living had a functional disability. The adapted Telephone Interview of Cognitive Status evaluated cognitive function. Persons with scores <7 had a CICD. Healthcare provider dementia-related diagnosis was self-reported. Undiagnosed CICD was defined as no reported dementia-related diagnosis but had CICD, while diagnosed CICD was classified as reporting a dementia-related diagnosis. Covariate-adjusted logistic models were used for the analyses.

resultsPersons with undiagnosed CICD had 1.37 (95% confidence interval (CI): 1.04-1.80) greater odds for weakness and 2.02 (CI: 1.39-2.94) greater odds for slow gait speed. Older adults with diagnosed CICD had 2.29 (CI: 1.32-3.97) greater odds for slowness and 1.85 (CI: 1.19-2.90) greater odds for functional disability.

conclusionScreening for CICD could be recommended when defects in physical function are observed in older adults.

Indexed as

Cognitive DysfunctionDementiaActivities of Daily LivingAgedFemaleHand StrengthHumansMaleWalking SpeedActivities of daily livingagingcognitive dysfunctiongeriatric assessmentgeriatricshand strengthwalking speed

Identifiers

PMID35912741
PMCPMC10171085
OpenAlexW4288042416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.