Evidence map›Paper›PMID 35912578›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Ligand-based design, synthesis, computational insights, and

Mohamed Elagawany, Ayman Abo Elmaaty, Ahmed Mostafa, Noura M Abo Shama, Eman Y Santali, Bahaa Elgendy, Ahmed A Al-Karmalawy

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Consensus Pharmacophore Strategy For Identifying Novel SARS-Cov-2 MJournal of chemical information and modeling · 2024
    Article
  9. Biological evaluation, docking studies, andJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Anticoagulants as Potential SARS-CoV-2 MInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed ElagawanyDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt.ORCID 0000-0002-1597-5324
Ayman Abo ElmaatyDepartment of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Port Said, Egypt.
Ahmed MostafaCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Cairo, Egypt.
Noura M Abo ShamaCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Cairo, Egypt.
Eman Y SantaliDepartment of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif, Saudi Arabia.
Bahaa ElgendyCenter for Clinical Pharmacology, Washington University School of Medicine, University of Health Sciences, St. Louis, MO, USA.
Ahmed A Al-KarmalawyDepartment of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, Egypt.ORCID 0000-0002-8173-6073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt development of new effective therapeutic interventions for the battle against SARS-CoV-2. A new series of

Indexed as

COVID-19 Drug TreatmentPandemicsCoronavirus 3C ProteasesCysteine EndopeptidasesHumansLigandsMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsSARS-CoV-2Viral Nonstructural Proteins3C-like proteinase, SARS-CoV-2Coronavirus 3C ProteasesCysteine EndopeptidasesLigandsProtease InhibitorsViral Nonstructural Proteinsanti-SARS-CoV-2 Mproin silicoin vitroN-(5-nitrothiazol-2-yl)-carboxamido derivativesSAR

Identifiers

PMID35912578
PMCPMC9344964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.