ArticleChemistry (Weinheim an der Bergstrasse, Germany)2022
In situ Grignard Metalation Method, Part II: Scope of the One-Pot Synthesis of Organocalcium Compounds.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 12 citations in OpenAlex.
- Comparison of MgYb and Mg-Ca bonding: structures, electronic analyses and reactivities.Chemical science · 2026Article
- Synthesis of Heteroleptic Amidinato Calcium Halides via the In-Situ Grignard Addition Method (iGAM) Complementing the Metalation of Amidines.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Opportunities with calcium Grignard reagents and other heavy alkaline-earth organometallics.Nature reviews. Chemistry · 2023Review
- In situ Grignard Metalation Method, Part II: Scope of the One-Pot Synthesis of Organocalcium Compounds.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
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6 authors at 1 institution in 1 country.
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Abstract
The in situ Grignard Metalation Method (iGMM) is a straightforward one-pot strategy to synthesize alkaline-earth metal amides in multi-gram scale with high yields via addition of bromoethane to an ethereal suspension of a primary or secondary amine and magnesium (Part I) or calcium (Part II). This method is highly advantageous because no activation of calcium is required prior to the reaction. Contrary to the magnesium-based iGMM, there are some limitations, the most conspicuous one is the large influence of steric factors. The preparation of Ca(hmds)
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