Evidence map›Paper›PMID 35912357›Full record

ArticleACS central science2022

Asymmetric Syntheses of (+)- and (-)-Collybolide Enable Reevaluation of

Sophia L Shevick, Stephan M Freeman, Guanghu Tong, Robin J Russo, Laura M Bohn, Ryan A Shenvi

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sophia L ShevickDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID https://orcid.org/0000-0003-1703-5448
Stephan M FreemanDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Guanghu TongDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Robin J RussoDepartment of Molecular Medicine, Scripps Research, 130 Scripps Way, Jupiter, Florida 33458, United States.
Laura M BohnDepartment of Molecular Medicine, Scripps Research, 130 Scripps Way, Jupiter, Florida 33458, United States.ORCID https://orcid.org/0000-0002-6474-8179
Ryan A ShenviDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID https://orcid.org/0000-0001-8353-6449
Scripps Institution of Oceanography · USScripps Research Institute · US

Funding

Novel Probes of the Kappa Opioid Receptor: Chemistry, Pharmacology, and BiologyR01DA031927 · NIDA · UNIVERSITY OF SOUTH FLORIDA · PI Jeffrey Aube, Laura M. Bohn · 2011 to 2026
$8.4M
Unusual Pharmacophores and New Tools for Cross-CouplingR35GM122606 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI Ryan Ashok Shenvi · 2017 to 2026
$7.1M
Biased Kappa Opioid Agonists as Non-addictive AnalgesicsR01DA048490 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI JONES, SARA RAULERSON, MARTIN, THOMAS JEFFREY · 2019 to 2023
$3.4M
NRSA Training CoreTL1TR002551 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TEYTON, LUC · 2018 to 2022
$1.2M
NCATS NIH HHS TL1 TR002551NIDA NIH HHS R01 DA031927NIDA NIH HHS R01 DA048490NIGMS NIH HHS R35 GM122606
6 · The paper itself

Abstract

The fungal metabolite collybolide has attracted attention as a non-nitrogenous, potent, and biased agonist of the

Identifiers

PMID35912357
PMCPMC9335922
OpenAlexW4285800360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.