Evidence map›Paper›PMID 35912135›Full record

ArticleBrain communications2022

Disentangling dyskinesia from parkinsonism in motor structures of patients with schizophrenia.

Katrin Sakreida, Wei-Hua Chiu, Juergen Dukart, Simon B Eickhoff, Thomas Frodl, Christian Gaser, Michael Landgrebe, Berthold Langguth, Daniela Mirlach, Ioana-Sabina Rautu and 2 more

Abstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katrin SakreidaDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.ORCID https://orcid.org/0000-0002-1228-3162
Wei-Hua ChiuDepartment of Neurology, Grossman School of Medicine, New York University, New York, NY 10017, USA.
Juergen DukartInstitute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich 52425, Germany.
Simon B EickhoffInstitute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich 52425, Germany.ORCID https://orcid.org/0000-0001-6363-2759
Thomas FrodlDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.
Christian GaserDepartment of Neurology, Jena University Hospital, Jena 07747, Germany.
Michael LandgrebeDepartment of Psychiatry, Psychotherapy and Psychosomatics, kbo-Lech-Mangfall-Klinik Agatharied, Hausham 83734, Germany.
Berthold LangguthDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg 93053, Germany.
Daniela MirlachDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg 93053, Germany.
Ioana-Sabina RautuUnité de Recherche en Neurosciences Cognitives (UNESCOG), Center for Research in Cognition and Neurosciences (CRCN), Université Libre de Bruxelles (ULB), Brussels 1050, Belgium.ORCID https://orcid.org/0000-0002-0631-6044
Markus WittmannDepartment of Psychiatry, Psychosomatics and Psychotherapy, District Hospital Wöllershof, Störnstein 92721, Germany.
Timm B PoepplDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.ORCID https://orcid.org/0000-0002-5992-5695

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with schizophrenia frequently suffer from motor abnormalities, but underlying alterations in neuroarchitecture remain unclear. Here, we aimed to disentangle dyskinesia from parkinsonism in motor structures of patients with schizophrenia and to assess associated molecular architecture. We measured grey matter of motor regions and correlated volumetric estimates with dyskinesia and parkinsonism severity. Associations with molecular architecture were identified by cross-modal spatial correlations between ensuing maps of abnormality-related volume alterations and neurotransmitter maps from healthy populations. Both phenomena were linked to (specific) striatal and basal forebrain reductions as well as to D

Indexed as

grey matter volumemagnetic resonance imagingmotor symptomsneurotransmittersschizophrenia

Identifiers

PMID35912135
PMCPMC9337227

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.