Evidence map›Paper›PMID 35912076›Full record

ArticleFrontiers in aging neuroscience2022

Soft Attention Based DenseNet Model for Parkinson's Disease Classification Using SPECT Images.

Mahima Thakur, Harisudha Kuresan, Samiappan Dhanalakshmi, Khin Wee Lai, Xiang Wu

Abstract read
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Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Detection of parkinson's disease with neuroimaging modalities using machine learning and artificial intelligence: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Mahima ThakurDepartment of Electronics and Communication Engineering, SRM Institute of Science and Technology, Chennai, India.
Harisudha KuresanDepartment of Electronics and Communication Engineering, SRM Institute of Science and Technology, Chennai, India.
Samiappan DhanalakshmiDepartment of Electronics and Communication Engineering, SRM Institute of Science and Technology, Chennai, India.
Khin Wee LaiDepartment of Biomedical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.
Xiang WuSchool of Medical Information Engineering, Xuzhou Medical University, Xuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Deep learning algorithms have long been involved in the diagnosis of severe neurological disorders that interfere with patients' everyday tasks, such as Parkinson's disease (PD). The most effective imaging modality for detecting the condition is DaTscan, a variety of single-photon emission computerized tomography (SPECT) imaging method. The goal is to create a convolutional neural network that can specifically identify the region of interest following feature extraction. Methods: The study comprised a total of 1,390 DaTscan imaging groups with PD and normal classes. The architecture of DenseNet-121 is leveraged with a soft-attention block added before the final classification layer. For visually analyzing the region of interest (ROI) from the images after classification, Soft Attention Maps and feature map representation are used. Outcomes: The model obtains an overall accuracy of 99.2% and AUC-ROC score 99%. A sensitivity of 99.2%, specificity of 99.4% and f1-score of 99.1% is achieved that surpasses all prior research findings. Soft-attention map and feature map representation aid in highlighting the ROI, with a specific attention on the putamen and caudate regions. Conclusion: With the deep learning framework adopted, DaTscan images reveal the putamen and caudate areas of the brain, which aid in the distinguishing of normal and PD cohorts with high accuracy and sensitivity.

Indexed as

area under the curveDenseNet architectureneural networksParkinson’s disease (PD)region of convergence (ROC)

Identifiers

PMID35912076
PMCPMC9326232

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.