Evidence map›Paper›PMID 35911884›Full record

ArticleFrontiers in neurology2022

Association Between Previous Stroke and Severe COVID-19: A Retrospective Cohort Study and an Overall Review of Meta-Analysis.

Huayao Huang, Junnian Chen, Shuangfang Fang, Xiaoling Chen, Xiaobin Pan, Hanhan Lei, Yixian Zhang, Hailong Lin, Qilin Yuan, Pincang Xia and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Huayao HuangDepartment of Rehabilitation, Fujian Medical University Union Hospital, Fuzhou, China.
Junnian ChenDepartment of Critical Care Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Shuangfang FangDepartment of Neurology, Stroke Research Center, Fujian Medical University Union Hospital, Fuzhou, China.
Xiaoling ChenDepartment of Infectious Disease, Fujian Medical University Union Hospital, Fuzhou, China.
Xiaobin PanDepartment of Critical Care Medicine, Fujian Provincial Hospital South Branch, Fuzhou, China.
Hanhan LeiDepartment of Neurology, Stroke Research Center, Fujian Medical University Union Hospital, Fuzhou, China.
Yixian ZhangDepartment of Rehabilitation, Fujian Medical University Union Hospital, Fuzhou, China.
Hailong LinDepartment of Radiology, Fujian Medical University Union Hospital, Fuzhou, China.
Qilin YuanDepartment of Neurology, Stroke Research Center, Fujian Medical University Union Hospital, Fuzhou, China.
Pincang XiaFujian Center for Disease Control and Prevention, Fuzhou, China.
Nan LiuDepartment of Rehabilitation, Fujian Medical University Union Hospital, Fuzhou, China.
Houwei DuDepartment of Neurology, Stroke Research Center, Fujian Medical University Union Hospital, Fuzhou, China.
Fujian Medical University · CNUnion Hospital · CNFujian Provincial Hospital · CNGansu Provincial Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to investigate the association between previous stroke and the risk of severe coronavirus disease 2019 (COVID-19). Methods: We included 164 (61.8 ± 13.6 years) patients with COVID-19 in a retrospective study. We evaluated the unadjusted and adjusted associations between previous stroke and severe COVID-19, using a Cox regression model. We conducted an overall review of systematic review and meta-analysis to investigate the relationship of previous stroke with the unfavorable COVID-19 outcomes. Results: The rate of severe COVID-19 in patients with previous stroke was 28.37 per 1,000 patient days (95% confidence interval [CI]: 10.65-75.59), compared to 3.94 per 1,000 patient days (95% CI: 2.66-5.82) in those without previous stroke ( Conclusion: Previous stroke seems to influence the course of COVID-19 infection; such patients are at high risk of severe COVID-19 and might benefit from early hospital treatment measures and preventive strategies.

Indexed as

cerebrovascular diseasecoronavirus disease 2019outcomeoverall reviewstroke

Identifiers

PMID35911884
PMCPMC9327441
OpenAlexW4285089419

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.