Evidence map›Paper›PMID 35911854›Full record

ArticleInternational journal of reproductive biomedicine2022

The effect of hyperbaric oxygen therapy in the inflammatory response in a mouse model of endometriosis: An experimental study.

Dedy Syahrizal, Cut Mustika, Nanda Ayu Puspita, Mohammad Guritno Suryokusumo, Hendy Hendarto

Abstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dedy SyahrizalDepartment of Biochemistry, Medical Faculty, Universitas Syiah Kuala, Banda Aceh, Indonesia.ORCID https://orcid.org/0000-0002-1908-3155
Cut MustikaDepartment of Public Health, Medical Faculty, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Nanda Ayu PuspitaDepartment of Biochemistry, Medical Faculty, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Mohammad Guritno SuryokusumoMedical Hyperbaric Study Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Hendy HendartoDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endometriosis pathogenesis is related to the inflammation shown by the secretion of pro-inflammatory mediators. This hypoxia condition can stimulate this condition. Objective: To investigate the effect of hyperbaric oxygen therapy (HBOT) on the inflammation reaction of endometriosis-induced mice. Materials and Methods: The animals were designated into 3 groups: I) the pre-test group, II) the post-test group receiving the HBOT, and III) the post-test group without HBOT. All groups were subjected to induction of endometriosis by xenotransplantation for 15 days. HBOT was given 30 min 3 times a day for 10 days. The evaluation of the HBOT effect was conducted by examining the endometrial tissue. The inflammation level was evaluated using the Klopfleisch semiquantitative scoring system (index remmele scale), whilst the expression of nuclear factor kappa (NF Results: The results showed that group I demonstrated the highest level of inflammation degree (9.41 Conclusion: HBOT significantly reduced the inflammation level on the endometrial lesion in mice, involving the NF

Indexed as

EndometriosisHyperbaric oxygenationHypoxiaInflammationMouse.

Identifiers

PMID35911854
PMCPMC9334893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.