Evidence map›Paper›PMID 35911834›Full record

ArticleFrontiers in pediatrics2022

Relevance of Intestinal Microbiota in Immunoglobulin A Vasculitis With Abdominal Involvement.

Linqian Zhang, Xinyi Jia, Panjian Lai, Kang Wang, Yunguang Bao, Xiaobing Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Linqian ZhangJinhua Maternal and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, China.
Xinyi JiaJinhua Maternal and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, China.
Panjian LaiJinhua Maternal and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, China.
Kang WangJinhua Maternal and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, China.
Yunguang BaoJinhua Maternal and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, China.
Xiaobing LiJinhua Maternal and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, China.
Children's Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We explored the intestinal microbiota changes in IgAV with abdominal involvement (IgAV-GI) at the acute and convalescent stages and evaluated the role of intestinal microbiota in the clinical course of patients with IgAV. Methods: A total of 37 patients with IgAV were included, and the control group comprised 37 age- and sex-matched healthy children. Stool samples were collected from 28 children with IgAV-GI (19 in the acute stage and 9 in the recovery stage) and from nine children with non-abdominal involvement. Fecal specimens were selected and DNA was obtained using an extraction kit which was then subjected to high-throughput sequencing and analysis. Results: There was no significant difference in the community structure of the intestinal microbiota among the IgAV-GI acute, IgAV-GI convalescence, and IgAV-non-GI stages. The abundance of Conclusion: Different bacterial species may be involved in the pathogenesis of different types of IgAV-GI. Differences were observed in the intestinal microbiota between healthy children and children with IgAV.

Indexed as

BacteroidesBifidobacteriumimmunoglobulin A vasculitis with abdominal involvementintestinal microbiota high-throughput sequencingRuminococcusVeillonella

Identifiers

PMID35911834
PMCPMC9329519
OpenAlexW4285388883

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.