Evidence map›Paper›PMID 35911824›Full record

ArticleFrontiers in pediatrics2022

Vitamin D Supplementation: Association With Serum Cytokines in Pediatric Hematopoietic Stem Cell Transplantation.

Braden Olsen, Jessica Bodea, Angela Garcia, Kristen Beebe, Courtney Campbell, Carly Schwalbach, Dana Salzberg, Holly Miller, Roberta Adams, Lucia Mirea and 5 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03176849 (A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03176849 phase4completednot on this map

A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 (Stoss Therapy) in Pediatric Patients Undergoing HSCT to Prevent Vitamin D Deficiency and Insufficiency During Transplant

TypeinterventionalSponsorPhoenix Children's HospitalRan2017 to 2019Enrolled49ConditionsVitamin D Deficiency, Stem Cell Transplant Complications, Pediatric Cancer, Blood DisorderArmsVitamin D3, Standard Vitamin D3 Supplementation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Braden OlsenCreighton School of Medicine, Phoenix, AZ, United States.
Jessica BodeaSt. Jude Children's Research Hospital, Memphis, TN, United States.
Angela GarciaCreighton School of Medicine, Phoenix, AZ, United States.
Kristen BeebePhoenix Children's Hospital, Phoenix, AZ, United States.
Courtney CampbellPhoenix Children's Hospital, Phoenix, AZ, United States.
Carly SchwalbachPhoenix Children's Hospital, Phoenix, AZ, United States.
Dana SalzbergPhoenix Children's Hospital, Phoenix, AZ, United States.
Holly MillerPhoenix Children's Hospital, Phoenix, AZ, United States.
Roberta AdamsPhoenix Children's Hospital, Phoenix, AZ, United States.
Lucia MireaPhoenix Children's Hospital, Phoenix, AZ, United States.
Paul CastilloUF Health Shands Children's Hospital, Gainesville, FL, United States.
Biljana HornUF Health Shands Children's Hospital, Gainesville, FL, United States.
Sandhya BansalSt. Joseph's Hospital & Medical Center, Phoenix, AZ, United States.
Thalachallour MohanakumarSt. Joseph's Hospital & Medical Center, Phoenix, AZ, United States.
Alexander NgwubeCreighton School of Medicine, Phoenix, AZ, United States.
Phoenix Children's Hospital · USMayo Clinic Hospital · USCreighton University · USSt. Joseph's Hospital and Medical Center · USUF Health Shands Hospital · USSt. Jude Children's Research Hospital · US

Funding

Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
NCATS NIH HHS KL2 TR001429
6 · The paper itself

Abstract

Vitamin D deficiency is prevalent in pediatric patients presenting for hematopoietic stem cell transplantation (HSCT) and has been linked to poor clinical outcomes. Using the data from a randomized control trial, in this paper we explore the effects of vitamin D supplementation on circulating cytokine levels during pediatric HSCT (www.clinicaltrials.gov as NCT03176849). A total of 41 children, 20 received Stoss therapy and 21 children received standard of care vitamin D supplementation. Levels of 25(OH)D and 20 cytokines were assessed at baseline and day +30. Significantly (

Indexed as

cytokine-immunological termshematopoietic cell transplantationpediatrictransplant complicationsvitamin D

Identifiers

PMID35911824
PMCPMC9326107
OpenAlexW4285395821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.