Evidence map›Paper›PMID 35911517›Full record

ArticleFrontiers in cardiovascular medicine2022

Early Results of a Novel Hybrid Prosthesis for Treatment of Acute Aortic Dissection Type A With Distal Anastomosis Line Beyond Aortic Arch Zone Zero.

Arash Mehdiani, Yukiharu Sugimura, Louise Wollgarten, Moritz Benjamin Immohr, Sebastian Bauer, Hubert Schelzig, Markus Udo Wagenhäuser, Gerald Antoch, Artur Lichtenberg, Payam Akhyari

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06044259 (Randomized Trial on Acutely Dissected Aorta Repair With Hemiarch Replacement With or Without Stent Implantation), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06044259 narecruitingnot on this mapstarted 2023, after this paper: background citation

Randomized Trial on Acutely Dissected Aorta Repair With Hemiarch Replacement With or Without Stent Implantation (RADAR Trial)

TypeinterventionalSponsorChinese University of Hong KongRan2023 to 2027Enrolled72ConditionsAortic DissectionArmsAMDS, Artivion, Atlanta, Georgia, US, Conventional hemiarch replacement
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arash MehdianiDepartment of Cardiac Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Yukiharu SugimuraDepartment of Cardiac Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Louise WollgartenDepartment of Cardiac Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Moritz Benjamin ImmohrDepartment of Cardiac Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Sebastian BauerDepartment of Cardiac Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Hubert SchelzigDepartment of Vascular and Endovascular Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Markus Udo WagenhäuserDepartment of Vascular and Endovascular Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Gerald AntochDepartment of Diagnostic and Interventional Radiology, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Artur LichtenbergDepartment of Cardiac Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.
Payam AkhyariDepartment of Cardiac Surgery, Heinrich Heine University Duesseldorf, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute aortic dissection type A (AADA) is associated with high perioperative morbidity and mortality. A novel non-covered hybrid prosthesis (Ascyrus Medical Dissection Stent (AMDS) Hybrid Prosthesis, Cryolife/Jotec, Hechingen, Germany) can be easily implanted to stabilize the true lumen (TL), improve remodeling, and preserve organ perfusion. Although developed for implantation in aortic zone 0, occasionally, partial replacement of the aortic arch and further distal implantation of AMDS may appear favorable. Implantation of AMDS with anastomosis line beyond zone 0 has not been described yet. Materials and Methods: Between 08/2019 and 12/2020, a total of Results: None of the surviving patients (87.5%) showed signs of clinical malperfusion (i.e., stroke, spinal cord injury, and need for dialysis). A postoperative CT scan showed an open TL in all patients. The proportion of TL with respect to total aortic diameter (TL+FL) was postoperatively significantly higher in zone III ( Conclusion: Implantation of AMDS can be safely performed in patients who need partial replacement of the aortic arch beyond zone 0. The advantages of the AMDS can be combined with those of the total arch repair (remodeling of the arch and prevention of TL collapse) without the possible disadvantages (risk of spinal cord injury).

Indexed as

acute aortic dissection type A (AADA)AMDSaortic remodelingfrozen elephant trunkhemiarch and aortic arch replacement

Identifiers

PMID35911517
PMCPMC9329696

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.